James Craig Forrest, PhD

Research Program: Cancer Biology Faculty Rank: Associate Professor Campus: University of Arkansas for Medical Sciences College: College of Medicine Department: Microbiology & Immunology Faculty

Cancer Research Interest

• Disease Site Focus: Leukemia/ Lymphoma
• Research Focus Area: Prevention, Carcinogenesis
• Type of Research: Basic

Contact Information

• Email Address: JCFORREST@UAMS.EDU
• Profiles Research Networking Software: View Profile

Active Grants

• NIH/Nat. Inst. of Allergy & Infectious Diseases – 1R01AI181787
  “Defining KSHV LANA functions in viral pathogenesis and immune evasion”
  Principal Investigator
  7/1/2024 – 5/31/2029
• NIH/Nat. Inst. of Dental & Craniofacial Research – 1R03DE031978
  “Targeting ILlRAP in virus-associated malignancies”
  Principal Investigator
  5/1/2022 – 4/30/2025
• NIH/Nat. Cancer Institute – 2R01CA167065
  “Defining mechanisms of gammaherpesvirus-driven genomic instability in B cells”
  Principal Investigator
  3/11/2022 – 2/28/2027

Recent Publications

• Smith KR, Paul S, Dong Q, [et al., including Forrest JC]. Uracil-DNA glycosylase of murine gammaherpesvirus 68 binds cognate viral replication factors independently of its catalytic residues. mSphere. 2023:e0027823. PMID: 37747202. PMCID: PMC10597349.
• Allen JL, Amick BC 3rd, Williams ML, [et al., including Forrest JC]. A longitudinal study of SARS-CoV-2 antibody seroprevalence and mitigation behaviors among college students at an Arkansas University. Journal of American college health : J of ACH. 2023:1-10. PMID: 37289962.
• Karger AB, Brien JD, Christen JM, [et al., including Forrest JC]. The Serological Sciences Network (SeroNet) for COVID-19: Depth and Breadth of Serology Assays and Plans for Assay Harmonization. mSphere. 2022:e0019322. PMID: 35703544. PMCID: PMC9429934.
• Wilkins H, Jastaniah E, Spray B, [et al., including Forrest JC]. Seroprevalence of SARS-CoV-2 antibodies in front-line pediatric health care workers. Journal of the American College of Emergency Physicians open. 2022 3(3):e12743. PMID: 35601650. PMCID: PMC9110875.
• Gupta A, Owens SM, Oldenburg DG, [et al., including Forrest JC]. Lytic Replication and Reactivation from B Cells Is Not Required for Establishing or Maintaining Gammaherpesvirus Latency In Vivo. Journal of virology. 2022:e0069022. PMID: 35647668. PMCID: PMC9215232.
• Kennedy JL, Forrest JC, Young SG, [et al.]. Temporal Variations in Seroprevalence of Severe Acute Respiratory Syndrome Coronavirus 2 Infections by Race and Ethnicity in Arkansas. Open forum infectious diseases. 2022 9(5):ofac154. PMID: 35493126. PMCID: PMC9045955.
• Dai L, Lu YC, Chen J, [et al., including Forrest JC]. Oral Shedding of an Oncogenic Virus Alters the Oral Microbiome in HIV+ Patients. Frontiers in microbiology. 2022 13:882520. PMID: 35516440. PMCID: PMC9063630.
• Cardenas VM, Kennedy JL, Williams M, [et al., including Forrest JC]. State-wide random seroprevalence survey of SARS-CoV-2 past infection in a southern US State, 2020. PloS one. 2022 17(4):e0267322. PMID: 35476717. PMCID: PMC9045671.
• Arthur JM, Forrest JC, Boehme KW, [et al.]. Development of ACE2 autoantibodies after SARS-CoV-2 infection. PloS one. 2021 16(9):e0257016. PMID: 34478478. PMCID: PMC8415618.
• Owens SM, Oldenburg DG, White DW, Forrest JC. Deletion of Murine Gammaherpesvirus Gene M2 in Activation-Induced Cytidine Deaminase-Expressing B Cells Impairs Host Colonization and Viral Reactivation. Journal of virology. 2020. PMID: 33028711. PMCID: PMC7737732.
• Wongsurawat T, Gupta A, Jenjaroenpun P, [et al., including Forrest JC]. Author Correction: R-loop-forming Sequences Analysis in Thousands of Viral Genomes Identify A New Common Element in Herpesviruses. Scientific reports. 2020 10(1):12173. PMID: 32678142. PMCID: PMC7368006.
• Dai L, Jung BG, Chen J, [et al., including Forrest JC]. The potential impacts of early secreted antigenic target of 6 kDa of Mycobacterium tuberculosis on KSHV-infected cells. Journal of medical virology. 2020. PMID: 32648938. PMCID: PMC7796979.
• Chen J, Goyal N, Dai L, [et al., including Forrest J]. Developing new ceramide analogs and identifying novel sphingolipid-controlled genes against a virus-associated lymphoma. Blood. 2020. PMID: 32518949. PMCID: PMC7645984.
• Dai L, Forrest J, Barrett L, [et al.]. Porphyromonas gingivalis coinfects with KSHV in oral cavities of HIV+ patients and induces viral lytic reactivation. Journal of medical virology. 2020. PMID: 32436999. PMCID: PMC7679274.
• Wongsurawat T, Gupta A, Jenjaroenpun P, [et al., including Forrest JC]. R-loop-forming Sequences Analysis in Thousands of Viral Genomes Identify A New Common Element in Herpesviruses. Scientific reports. 2020 10(1):6389. PMID: 32286400. PMCID: PMC7156643.
• Dai L, Forrest J, Qiao J, [et al.]. Kaposi Sarcoma-Associated Herpesvirus and Staphylococcus aureus Coinfection in Oral Cavities of HIV-Positive Patients: A Unique Niche for Oncogenic Virus Lytic Reactivation. The Journal of infectious diseases. 2020 221(8):1331-1341. PMID: 31111897. PMCID: PMC7325796.
• Chen J, Forrest J, post s, [et al.]. Mechanistic Insights into Chemoresistance Mediated by Oncogenic Viruses in Lymphomas. Viruses. 2019 11(12). PMID: 31888174. PMCID: PMC6950054.