Arny Ferrando, PhD

Research Program: Cancer Therapeutics Faculty Rank: Professor Campus: University of Arkansas for Medical Sciences College: College of Medicine Department: Geriatrics

Cancer Research Interest

• Disease Site Focus: GU, Head and Neck
• Research Focus Area: Detection
• Type of Research: Clinical

Contact Information

• Email Address: AFERRANDO@UAMS.EDU
• Profiles Research Networking Software: View Profile

Active Grants

• National Cattlemen's Beef Association – NA
  “PostMenopause NCBA”
  Co-Investigator
  01/01/23 – 01/01/25
• National Cattlemen's Beef Association – NA
  “Time-Restricted Feeding NCBA”
  Co-Investigator
  10/01/22 – 09/30/24
• U.S. Army Research Institute of Environmental Medicine – W81XWH1C0067
  “Breakpoint”
  Principal Investigator
  03/29/21 – 09/28/23
• U.S. Army Research Institute of Environmental Medicine – W81XWH1820021
  “Ferrando - Warfighter Recovery Nutrition: Optimizing Protein Quantity, Quality, and Combat Ration Delivery Systems”
  Principal Investigator
  07/01/18 – 06/30/23

Publications

• Varanoske AN, Harris MN, Hebert C, [et al., including Ferrando AA]. Bioelectrical impedance phase angle is associated with physical performance before but not after simulated multi-stressor military operations. Physiological reports. 2023 11(6):e15649. PMID: 36949577. PMCID: PMC10033850.
• Smith-Ryan AE, Hirsch KR, Cabre HE, [et al., including Ferrando AA]. Menopause Transition - A Cross-Sectional Evaluation on Muscle Size and Quality. Medicine and science in sports and exercise. 2023. PMID: 36878186.
• Drummer DJ, Lavin KM, Graham ZA, [et al., including Ferrando AA]. Muscle transcriptomic circuits linked to periarticular physiology in end-stage osteoarthritis. Physiological genomics. 2022 54(12):501-513. PMID: 36278270. PMCID: PMC9762959.
• Wolfe RR, Kim IY, Park S, Ferrando A. Tracing metabolic flux to assess optimal dietary protein and amino acid consumption. Experimental & molecular medicine. 2022 54(9):1323-1331. PMID: 36075948. PMCID: PMC9534933.
• Berryman CE, McClung HL, Sepowitz JJ, [et al., including Ferrando AA]. Testosterone status following short-term, severe energy deficit is associated with fat-free mass loss in U.S. Marines. Physiological reports. 2022 10(18):e15461. PMID: 36117330. PMCID: PMC9483439.
• Varanoske AN, Harris MN, Hebert C, [et al., including Ferrando AA]. Testosterone undecanoate administration prevents declines in fat-free mass but not physical performance during simulated multi-stressor military operations. Journal of applied physiology (Bethesda, Md. : 1985). 2022 133(2):426-442. PMID: 35796614. PMCID: PMC9359646.
• Hirsch KR, Church DD, Wolfe RR, Ferrando AA. Continuous oral stable isotope ingestion to measure whole-body protein turnover. Clinical nutrition ESPEN. 2022 49:385-389. PMID: 35623841.
• Drummer DJ, McAdam JS, Seay R, [et al., including Ferrando AA]. Perioperative Assessment of Muscle Inflammation Susceptibility in Patients with End-Stage Osteoarthritis. Journal of applied physiology (Bethesda, Md. : 1985). 2022. PMID: 35238652. PMCID: PMC8993516.
• Witard OC, Ferrando AA, Phillips SM. Celebrating the Professional Life of Professor Kevin D. Tipton (1961-2022). International journal of sport nutrition and exercise metabolism. 2022:1-4. PMID: 35219275.
• Gonzalez DE, McAllister MJ, Waldman HS, [et al., including Ferrando AA]. International society of sports nutrition position stand: tactical athlete nutrition. Journal of the International Society of Sports Nutrition. 2022 19(1):267-315. PMID: 35813846. PMCID: PMC9261739.
• Banks NF, Rogers EM, Church DD, [et al., including Ferrando AA]. The contributory role of vascular health in age-related anabolic resistance. Journal of cachexia, sarcopenia and muscle. 2021. PMID: 34951146. PMCID: PMC8818606.
• Coker MS, Schutzler SE, Park S, [et al., including Ferrando AA]. Equivalent servings of free-range reindeer promote greater net protein balance compared to commercial beef. International journal of circumpolar health. 2021 80(1):1897222. PMID: 33704030. PMCID: PMC7954490.
• Osburn SC, Vann CG, Church DD, [et al., including Ferrando AA]. Proteasome- and Calpain-Mediated Proteolysis, but Not Autophagy, Is Required for Leucine-Induced Protein Synthesis in C2C12 Myotubes. Physiologia. 2021 1(1):22-33. PMID: 34927140. PMCID: PMC8681867.
• Church DD, Schutzler SE, Wolfe RR, Ferrando AA. Perioperative amino acid infusion reestablishes muscle net balance during total hip arthroplasty. Physiological reports. 2021 9(18):e15055. PMID: 34558214. PMCID: PMC8461212.
• Varanoske AN, Harris MN, Hebert C, [et al., including Ferrando AA]. Effects of testosterone undecanoate on performance during multi-stressor military operations: A trial protocol for the Optimizing Performance for Soldiers II study. Contemporary clinical trials communications. 2021 23:100819. PMID: 34278044. PMCID: PMC8264529.
• Hirsch KR, Greenwalt CE, Cabre HE, [et al., including Ferrando AA]. Metabolic effects of high-intensity interval training and essential amino acids. European journal of applied physiology. 2021. PMID: 34427732.
• Hirsch KR, Wolfe RR, Ferrando AA. Pre- and Post-Surgical Nutrition for Preservation of Muscle Mass, Strength, and Functionality Following Orthopedic Surgery. Nutrients. 2021 13(5). PMID: 34063333. PMCID: PMC8156786.
• Park S, Church DD, Schutzler SE, [et al., including Ferrando AA]. Metabolic Evaluation of the Dietary Guidelines' Ounce Equivalents of Protein Food Sources in Young Adults: A Randomized Controlled Trial. The Journal of nutrition. 2021 151(5):1190-1196. PMID: 33693735. PMCID: PMC8112772.
• Margolis LM, Karl JP, Wilson MA, [et al., including Ferrando AA]. Metabolomic profiles are reflective of hypoxia-induced insulin resistance during exercise in healthy young adult males. American journal of physiology. Regulatory, integrative and comparative physiology. 2021. PMID: 33949213. PMCID: PMC8321788.
• Gohar A, Wei JY, Schutzler SE, [et al., including Ferrando AA]. Daily consumption of a specially formulated essential amino acid-based dietary supplement improves physical performance in older adults with low physical functioning. The journals of gerontology. Series A, Biological sciences and medical sciences. 2021. PMID: 33475727. PMCID: PMC8202157.
• Gwin JA, Church DD, Hatch-McChesney A, [et al., including Ferrando AA]. Essential amino acid-enriched whey enhances post-exercise whole-body protein balance during energy deficit more than iso-nitrogenous whey or a mixed-macronutrient meal: a randomized, crossover study. Journal of the International Society of Sports Nutrition. 2021 18(1):4. PMID: 33413462. PMCID: PMC7791816.
• Hirsch KR, Greenwalt CE, Saylor HE, [et al., including Ferrando AA]. High-intensity interval training and essential amino acid supplementation: Effects on muscle characteristics and whole-body protein turnover. Physiological reports. 2021 9(1):e14655. PMID: 33369879. PMCID: PMC7769174.
• Ruple BA, Godwin JS, Mesquita PHC, [et al., including Ferrando AA]. Myofibril and Mitochondrial Area Changes in Type I and II Fibers Following 10 Weeks of Resistance Training in Previously Untrained Men. Frontiers in physiology. 2021 12:728683. PMID: 34630147. PMCID: PMC8497692.
• Drummer D, McAdam J, Seay R, [et al., including Ferrando A]. Osteoarthritis Progression: Mitigation and Rehabilitation Strategies. Frontiers in rehabilitation sciences. 2021 2:724052. PMID: 36188773. PMCID: PMC9397730.
• Park S, Church DD, Starck C, [et al., including Ferrando AA]. Correction to: The impact of Hayward green kiwifruit on dietary protein digestion and protein metabolism. European journal of nutrition. 2020. PMID: 33306152. PMCID: PMC7900059.
• Church DD, Hirsch KR, Park S, [et al., including Ferrando AA]. Essential Amino Acids and Protein Synthesis: Insights into Maximizing the Muscle and Whole-Body Response to Feeding. Nutrients. 2020 12(12). PMID: 33276485. PMCID: PMC7760188.
• Hirsch KR, Church DD, Kim IY, [et al., including Ferrando AA]. Comparison of basal whole-body protein kinetics and muscle protein synthesis between young and older adults. Physiological reports. 2020 8(23):e14633. PMID: 33278070. PMCID: PMC7718838.
• Duarte-Rojo A, Bloomer PM, Rogers RJ, [et al., including Ferrando AA]. Introducing EL-FIT (Exercise & Liver FITness), a smartphone app to prehabilitate and monitor liver transplant candidates. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. 2020. PMID: 33232547.
• Chen HW, Ferrando A, White MG, [et al.]. Home-Based Physical Activity and Diet Intervention to Improve Physical Function in Advanced Liver Disease: A Randomized Pilot Trial. Digestive diseases and sciences. 2020 65(11):3350-3359. PMID: 31907774.
• Park S, Jang J, Choi MD, [et al., including Ferrando AA]. The Anabolic Response to Dietary Protein Is Not Limited by the Maximal Stimulation of Protein Synthesis in Healthy Older Adults: A Randomized Crossover Trial. Nutrients. 2020 12(11). PMID: 33114585. PMCID: PMC7693481.
• Wu H, Jang J, Dridi S, [et al., including Ferrando AA]. Net protein balance correlates with expression of autophagy, mitochondrial biogenesis, and fat metabolism-related genes in skeletal muscle from older adults. Physiological reports. 2020 8(19):e14575. PMID: 33063954. PMCID: PMC7556313.
• Park S, Church DD, Starck C, [et al., including Ferrando AA]. The impact of Hayward green kiwifruit on dietary protein digestion and protein metabolism. European journal of nutrition. 2020. PMID: 32970234. PMCID: PMC7900049.
• Gwin JA, Church DD, Wolfe RR, [et al., including Ferrando AA]. Muscle Protein Synthesis and Whole-Body Protein Turnover Responses to Ingesting Essential Amino Acids, Intact Protein, and Protein-Containing Mixed Meals with Considerations for Energy Deficit. Nutrients. 2020 12(8). PMID: 32824200. PMCID: PMC7469068.
• Wardle SL, Macnaughton LS, McGlory C, [et al., including Ferrando AA]. Human skeletal muscle metabolic responses to 6 days of high-fat overfeeding are associated with dietary n-3PUFA content and muscle oxidative capacity. Physiological reports. 2020 8(16):e14529. PMID: 32845565. PMCID: PMC7448800.
• Lin FP, Ferrando AA, Dennis RA, [et al.]. Exercise-Induced Hyperammonemia Does Not Precipitate Overt Hepatic Encephalopathy. Hepatology (Baltimore, Md.). 2020 72(2):778-780. PMID: 31997375.
• Gwin JA, Church DD, Hatch-McChesney A, [et al., including Ferrando AA]. Effects of high versus standard essential amino acid intakes on whole-body protein turnover and mixed muscle protein synthesis during energy deficit: A randomized, crossover study. Clinical nutrition (Edinburgh, Scotland). 2020. PMID: 32768315.
• Chen HW, Ferrando AA, Dunn MA, [et al.]. Cadence From Physical Activity Trackers for Monitoring of Home-Based Exercise Intensity in Advanced Liver Disease. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. 2020 26(5):718-721. PMID: 32145132.
• Park S, Church DD, Azhar G, [et al., including Ferrando AA]. Anabolic response to essential amino acid plus whey protein composition is greater than whey protein alone in young healthy adults. Journal of the International Society of Sports Nutrition. 2020 17(1):9. PMID: 32041644. PMCID: PMC7011510.
• Margolis LM, Wilson MA, Whitney CC, [et al., including Ferrando AA]. Acute hypoxia reduces exogenous glucose oxidation, glucose turnover, and metabolic clearance rate during steady-state aerobic exercise. Metabolism: clinical and experimental. 2020 103:154030. PMID: 31778707.
• Wolfe RR, Park S, Kim IY, [et al., including Ferrando AA]. Advances in stable isotope tracer methodology part 2: new thoughts about an "old" method-measurement of whole body protein synthesis and breakdown in the fed state. Journal of investigative medicine : the official publication of the American Federation for Clinical Research. 2020 68(1):11-15. PMID: 31554677.
• Mobley CB, Romero MA, Haun CT, [et al., including Ferrando AA]. LAT1 Protein Content Increases Following 12 Weeks of Resistance Exercise Training in Human Skeletal Muscle. Frontiers in nutrition. 2020 7:628405. PMID: 33521042. PMCID: PMC7840583.
• Wolfe RR, Park S, Kim IY, [et al., including Ferrando AA]. Reply to Letter to the Editor: "The intrinsically labeled protein approach is the preferred method to quantify the release of dietary protein-derived amino acids into the circulation". American journal of physiology. Endocrinology and metabolism. 2019 317(3):E435. PMID: 31423801.
• Church DD, Gwin JA, Wolfe RR, [et al., including Ferrando AA]. Mitigation of Muscle Loss in Stressed Physiology: Military Relevance. Nutrients. 2019 11(8). PMID: 31344809. PMCID: PMC6724061.
• Wolfe RR, Park S, Kim IY, [et al., including Ferrando AA]. Quantifying the contribution of dietary protein to whole body protein kinetics: examination of the intrinsically labeled proteins method. American journal of physiology. Endocrinology and metabolism. 2019 317(1):E74-E84. PMID: 30939051. PMCID: PMC6689738.
• Kim IY, Park S, Smeets ETHC, [et al., including Ferrando AA]. Consumption of a Specially-Formulated Mixture of Essential Amino Acids Promotes Gain in Whole-Body Protein to a Greater Extent than a Complete Meal Replacement in Older Women with Heart Failure. Nutrients. 2019 11(6). PMID: 31212940. PMCID: PMC6627910.
• Church DD, Pasiakos SM, Wolfe RR, Ferrando AA. Acute testosterone administration does not affect muscle anabolism. Nutrition & metabolism. 2019 16:56. PMID: 31440303. PMCID: PMC6704643.
• Parry HA, Mobley CB, Mumford PW, [et al., including Ferrando AA]. Bovine Milk Extracellular Vesicles (EVs) Modification Elicits Skeletal Muscle Growth in Rats. Frontiers in physiology. 2019 10:436. PMID: 31040795. PMCID: PMC6476979.
• Kim IY, Shin YA, Schutzler SE, [et al., including Ferrando AA]. Quality of meal protein determines anabolic response in older adults. Clinical nutrition (Edinburgh, Scotland). 2018 37(6 Pt A):2076-2083. PMID: 29066101. PMCID: PMC9987475.
• Pasiakos SM, Berryman CE, Carbone JW, [et al., including Ferrando AA]. Muscle Fn14 gene expression is associated with fat-free mass retention during energy deficit at high altitude. Physiological reports. 2018 6(14):e13801. PMID: 30009538. PMCID: PMC6046641.
• Margolis LM, Carbone JW, Berryman CE, [et al., including Ferrando AA]. Severe energy deficit at high altitude inhibits skeletal muscle mTORC1-mediated anabolic signaling without increased ubiquitin proteasome activity. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2018:fj201800163RR. PMID: 29878853.
• Kim IY, Schutzler S, Schrader AM, [et al., including Ferrando AA]. Protein intake distribution pattern does not affect anabolic response, lean body mass, muscle strength or function over 8 weeks in older adults: A randomized-controlled trial. Clinical nutrition (Edinburgh, Scotland). 2018 37(2):488-493. PMID: 28318687. PMCID: PMC9252263.
• Berryman CE, Young AJ, Karl JP, [et al., including Ferrando AA]. Severe negative energy balance during 21 d at high altitude decreases fat-free mass regardless of dietary protein intake: a randomized controlled trial. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2018 32(2):894-905. PMID: 29066613.
• Duarte-Rojo A, Ruiz-Margáin A, Montaño-Loza AJ, [et al., including Ferrando A]. Exercise and physical activity for patients with end-stage liver disease: Improving functional status and sarcopenia while on the transplant waiting list. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. 2018 24(1):122-139. PMID: 29024353.
• Berryman CE, Sepowitz JJ, McClung HL, [et al., including Ferrando AA]. Supplementing an energy adequate, higher protein diet with protein does not enhance fat-free mass restoration after short-term severe negative energy balance. Journal of applied physiology (Bethesda, Md. : 1985). 2017 122(6):1485-1493. PMID: 28385919.
• Kim IY, Schutzler SE, Azhar G, [et al., including Ferrando AA]. Short term elevation in dietary protein intake does not worsen insulin resistance or lipids in older adults with metabolic syndrome: a randomized-controlled trial. BMC nutrition. 2017 3. PMID: 28713581. PMCID: PMC5510665.
• Jäger R, Kerksick CM, Campbell BI, [et al., including Ferrando AA]. International Society of Sports Nutrition Position Stand: protein and exercise. Journal of the International Society of Sports Nutrition. 2017 14:20. PMID: 28642676. PMCID: PMC5477153.
• Ziegenfuss TN, Lopez HL, Kedia A, [et al., including Ferrando AA]. Effects of an amylopectin and chromium complex on the anabolic response to a suboptimal dose of whey protein. Journal of the International Society of Sports Nutrition. 2017 14:6. PMID: 28194093. PMCID: PMC5299635.