Charles M Quick, MD

Research Program: Cancer Therapeutics Faculty Rank: Associate Professor Campus: University of Arkansas for Medical Sciences College: College of Medicine Department: Pathology Clinical

Cancer Research Interest

• Research Interest Statement: I am a surgical pathologist that specializes in gynecologic and perinatal surgical pathology. My research focuses on precancerous lesions and tumor microenvironment of the gynecologic tract.

Contact Information

• Email Address: QUICKCHARLESM@UAMS.EDU
• Profiles Research Networking Software: View Profile

Active Grants

• NIH/Nat. Cancer Institute – 2R01CA143130
  “Understanding and Enhancing T-Cell Responses to High Risk Human Papillomaviruses-Renewal”
  Co-Investigator
  7/1/2021 – 6/30/2026

Recent Publications

• Ewing LE, Harpenau RJ, Skinner CM, [et al., including Quick CM]. Inter-strain variability in responses to a single administration of the cannabidiol-rich cannabis extract in mice. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2024 192:114909. PMID: 39128689. PMCID: PMC11381146.
• Ewing LE, Skinner CM, McGill MR, [et al., including Quick CM]. Human quad liver-on-chip system as a tool toward bridging the gap between animals and humans regarding toxicology and pharmacology of a cannabidiol-rich cannabis extract. Drug and chemical toxicology. 2024:1-8. PMID: 39155655.
• Fadare O, Fard EV, Bhargava R, [et al., including Quick CM]. The Malignant Potential of Ovarian Steroid Cell Tumors Revisited: A Multi-institutional Clinicopathologic Analysis of 115 Cases. The American journal of surgical pathology. 2024 48(5):570-580. PMID: 38512100.
• Bellone S, Jeong K, Halle MK, [et al., including Quick CM]. Integrated mutational landscape analysis of poorly differentiated high-grade neuroendocrine carcinoma of the uterine cervix. Proceedings of the National Academy of Sciences of the United States of America. 2024 121(17):e2321898121. PMID: 38625939. PMCID: PMC11046577.
• Mercado MAB, Li Q, Quick CM, [et al.]. BHLHE40 drives protective polyfunctional CD4 T cell differentiation in the female reproductive tract against Chlamydia. PLoS pathogens. 2024 20(1):e1011983. PMID: 38271477. PMCID: PMC10846703.
• Jeffus SK, Quick CM. Coexpression of p53 and p16 in Vulvar Squamous Neoplasia. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 2023 36(10):100319. PMID: 37708626.
• Campbell K, Quiroga EF, Dunn A, [et al., including Quick CM]. Eccrine Porocarcinoma of the Vulva With Sarcomatoid Transformation, a New Human Papillomavirus-associated Malignancy? Case Report and Review of the Literature. International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists. 2023. PMID: 37406346.
• Gama JM, Quick CM. Uterine alveolar soft part sarcoma - an unexpected case. International journal of gynecological cancer : official journal of the International Gynecological Cancer Society. 2023. PMID: 37146992.
• Alhallak I, Quick CM, Graham GL, Simmen RCM. A Pilot Study on the Co-existence of Diabetes and Endometriosis in Reproductive-Age Women: Potential for Endometriosis Progression. Reproductive sciences (Thousand Oaks, Calif.). 2023. PMID: 36788175. PMCID: PMC10354185.
• Lennerz JK, Pantanowitz L, Amin MB, [et al., including Quick CM]. Ensuring remote diagnostics for pathologists: an open letter to the US Congress. Nature medicine. 2022 28(12):2453-2455. PMID: 36266514.
• Hamza MA, Quick CM, Williams HR, [et al.]. HPV-associated Vulvar Intraepithelial Carcinoma With Sebaceous Differentiation: Report of 2 Cases. International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists. 2022. PMID: 36383010.
• Paidi SK, Troncoso JR, Raj P, [et al., including Quick CM]. Raman Spectroscopy and Machine Learning Reveals Early Tumor Microenvironmental Changes Induced by Immunotherapy. Cancer research. 2021. PMID: 34645610. PMCID: PMC8841097.
• Racher ML, Morris M, Scott AP, [et al., including Quick CM]. Placental location site and adverse antepartum pregnancy complications: a meta-analysis and review of the literature. Archives of gynecology and obstetrics. 2021. PMID: 34590170.
• Mercier AM, Zorn KK, Quick CM, Huffman LB. Recurrent gynandroblastoma of the ovary with germline DICER1 mutation: A case report and review of the literature. Gynecologic oncology reports. 2021 37:100806. PMID: 34169133. PMCID: PMC8207187.
• Troncoso JR, Diaz PM, Lee DE, [et al., including Quick CM]. Longitudinal monitoring of tumor response to immune checkpoint inhibitors using noninvasive diffuse reflectance spectroscopy. Biomedical optics express. 2021 12(7):3982-3991. PMID: 34457393. PMCID: PMC8367250.
• Choi J, Manzano A, Dong W, [et al., including Quick CM]. Integrated mutational landscape analysis of uterine leiomyosarcomas. Proceedings of the National Academy of Sciences of the United States of America. 2021 118(15). PMID: 33876771. PMCID: PMC8053980.
• Shibata T, Shah S, Evans T, [et al., including Quick CM]. Expansion of Human Papillomavirus-Specific T Cells in Periphery and Cervix in a Therapeutic Vaccine Recipient Whose Cervical High-Grade Squamous Intraepithelial Lesion Regressed. Frontiers in immunology. 2021 12:645299. PMID: 34659195. PMCID: PMC8515132.
• Johnsrud AJ, Jenkins SV, Jamshidi-Parsian A, [et al., including Quick CM]. Evidence for Early Stage Anti-Tumor Immunity Elicited by Spatially Fractionated Radiotherapy-Immunotherapy Combinations. Radiation research. 2020 194(6):688-697. PMID: 33348372. PMCID: PMC8008989.
• Jeffus SK, Quick CM, Chen C, [et al.]. Prospective Consensus Reporting by Gynecologic Pathology and Dermatopathology Improves Diagnosis of Vulvar Biopsies. Archives of pathology & laboratory medicine. 2020 144(12). PMID: 33212498.
• Kutanzi KR, Ewing LE, Skinner CM, [et al., including Quick CM]. Safety and Molecular-Toxicological Implications of Cannabidiol-Rich Cannabis Extract and Methylsulfonylmethane Co-Administration. International journal of molecular sciences. 2020 21(20). PMID: 33096940. PMCID: PMC7656295.
• Wright MF, Fitzlaff S, Wyeth A, [et al., including Quick CM]. Nuclear Beta-Catenin Expression in Endometrioid Intraepithelial Neoplasia (Atypical Hyperplasia) Does Not Predict Carcinoma on Subsequent Hysterectomy. International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists. 2020. PMID: 32897964.
• Sandlin AT, Magann EF, Ounpraseuth ST, [et al., including Quick CM]. A comparison of placental pathology between small for gestational age infants at < 5 % versus 5-9. European journal of obstetrics, gynecology, and reproductive biology. 2020 252:483-489. PMID: 32758859.
• Sangoi AR, Cox RM, Higgins JP, [et al., including Quick CM]. Non-invasive papillary urothelial carcinoma with 'micropapillary' architecture: clinicopathological study of 18 patients emphasising clinical outcomes. Histopathology. 2020. PMID: 32443178.
• Miousse IR, Tobacyk J, Quick CM, [et al.]. Reply to Flugge: the anti-metastatic potential of methionine restriction in melanoma. Carcinogenesis. 2020 41(3):390-391. PMID: 31140558. PMCID: PMC7221500.
• Whittington JR, Cummings KF, Ounpraseuth ST, [et al., including Quick CM]. Placental changes in diabetic pregnancies and the contribution of hypertension. The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians. 2020:1-9. PMID: 32075455.
• Kolin DL, Quick CM, Dong F, [et al.]. SMARCA4-deficient Uterine Sarcoma and Undifferentiated Endometrial Carcinoma Are Distinct Clinicopathologic Entities. The American journal of surgical pathology. 2020 44(2):263-270. PMID: 31567195.
• Skinner CM, Nookaew I, Ewing LE, [et al., including Quick CM]. Potential Probiotic or Trigger of Gut Inflammation - The Janus-Faced Nature of Cannabidiol-Rich Cannabis Extract. Journal of dietary supplements. 2020 17(5):543-560. PMID: 32400224. PMCID: PMC7470626.
• Pabona JMP, Burnett AF, Brown DM, [et al., including Quick CM]. Metformin Promotes Anti-tumor Biomarkers in Human Endometrial Cancer Cells. Reproductive sciences (Thousand Oaks, Calif.). 2020 27(1):267-277. PMID: 32046384. PMCID: PMC7077930.
• Whittington JR, Whitcombe DD, Eads LE, [et al., including Quick CM]. Signet Ring Cell Carcinoma with Lymphangitic Carcinomatosis in Pregnancy: A Case Report of an Unexpected Maternal Death and Review of the Literature. The American journal of case reports. 2019 20:1888-1891. PMID: 31844036. PMCID: PMC6930696.