Ricky D Edmondson, PhD

Research Program: Cancer Biology Faculty Rank: Associate Professor Campus: University of Arkansas for Medical Sciences College: College of Medicine Department: Internal Medicine

Cancer Research Interest

• Type of Research: Basic

Contact Information

• Email Address: RDEDMONDSON@UAMS.EDU
• Profiles Research Networking Software: View Profile

Active Grants

• NIH/National Institutes of Health – 2R44DK130702
  “Development of a Precision Medicine-based Diagnostic Tool for Membranous Nephropathy”
  Co-Investigator
  09/15/22 – 05/31/24
• NIH/Nat. Inst. of General Medical Sciences – 1R01GM141040
  “Discovery and Characterization of Novel Sepsis Proteome Biomarkers”
  Co-Investigator
  09/10/21 – 08/31/25

Publications

• Caza TN, Storey AJ, Hassen SI, [et al., including Edmondson RD]. Discovery of seven novel putative antigens in membranous nephropathy and membranous lupus nephritis identified by mass spectrometry. Kidney international. 2023. PMID: 36638888. PMCID: PMC9974866.
• Das BK, Wang L, Fujiwara T, [et al., including Edmondson R]. Transferrin receptor 1-mediated iron uptake regulates bone mass in mice via osteoclast mitochondria and cytoskeleton. eLife. 2022 11. PMID: 35758636. PMCID: PMC9352353.
• Li D, Yu X, Kottur J, [et al., including Edmondson RD]. Discovery of a dual WDR5 and Ikaros PROTAC degrader as an anti-cancer therapeutic. Oncogene. 2022. PMID: 35525905. PMCID: PMC9189076.
• Xu C, Meng F, Park KS, [et al., including Edmondson RD]. A NSD3-targeted PROTAC suppresses NSD3 and cMyc oncogenic nodes in cancer cells. Cell chemical biology. 2021. PMID: 34469831. PMCID: PMC8882712.
• Caza TN, Hassen SI, Kenan DJ, [et al., including Edmondson RD]. Transforming Growth Factor Beta Receptor 3 (TGFBR3)-Associated Membranous Nephropathy. Kidney360. 2021 2(8):1275-1286. PMID: 35369660. PMCID: PMC8676385.
• Ahn JH, Davis ES, Daugird TA, [et al., including Edmondson RD]. Phase separation drives aberrant chromatin looping and cancer development. Nature. 2021. PMID: 34163069. PMCID: PMC8647409.
• Fan H, Guo Y, Tsai YH, [et al., including Edmondson RD]. A conserved BAH module within mammalian BAHD1 connects H3K27me3 to Polycomb gene silencing. Nucleic acids research. 2021 49(8):4441-4455. PMID: 33823544. PMCID: PMC8096256.
• Al-Rabadi LF, Caza T, Trivin-Avillach C, [et al., including Edmondson R]. Serine Protease HTRA1 as a Novel Target Antigen in Primary Membranous Nephropathy. Journal of the American Society of Nephrology : JASN. 2021. PMID: 33952630. PMCID: PMC8425645.
• Xu C, Tsai YH, Galbo PM, [et al., including Edmondson RD]. Cistrome analysis of YY1 uncovers a regulatory axis of YY1:BRD2/4-PFKP during tumorigenesis of advanced prostate cancer. Nucleic acids research. 2021. PMID: 33849067. PMCID: PMC8136773.
• Li J, Galbo PM Jr, Gong W, [et al., including Edmondson RD]. ZMYND11-MBTD1 induces leukemogenesis through hijacking NuA4/TIP60 acetyltransferase complex and a PWWP-mediated chromatin association mechanism. Nature communications. 2021 12(1):1045. PMID: 33594072. PMCID: PMC7886901.
• Caza TN, Hassen SI, Kuperman M, [et al., including Edmondson R]. Neural cell adhesion molecule 1 is a novel autoantigen in membranous lupus nephritis. Kidney international. 2020. PMID: 33045259. PMCID: PMC8032825.
• Koss B, Boerma M, Shields BD, [et al., including Edmondson RD]. Epigenetic Control of Cdkn2a.Arf Protects Tumor-Infiltrating Lymphocytes from Metabolic Exhaustion. Cancer research. 2020. PMID: 33004350. PMCID: PMC7642172.
• Caza T, Hassen S, Dvanajscak Z, [et al., including Edmondson R]. NELL1 is a target antigen in malignancy-associated membranous nephropathy. Kidney international. 2020. PMID: 32828756. PMCID: PMC7895854.
• Storey AJ, Naceanceno KS, Lan RS, [et al., including Edmondson RD]. ProteoViz: a tool for the analysis and interactive visualization of phosphoproteomics data. Molecular omics. 2020. PMID: 32347222. PMCID: PMC7423749.
• Chua XY, Mensah T, Aballo T, [et al., including Edmondson RD]. Tandem Mass Tag Approach Utilizing Pervanadate BOOST Channels Delivers Deeper Quantitative Characterization of the Tyrosine Phosphoproteome. Molecular & cellular proteomics : MCP. 2020 19(4):730-743. PMID: 32071147. PMCID: PMC7124467.
• Chua XY, Mensah T, Aballo T, [et al., including Edmondson RD]. Tandem Mass Tag Approach Utilizing Pervanadate BOOST Channels Delivers Deeper Quantitative Characterization of the Tyrosine Phosphoproteome. Molecular & cellular proteomics : MCP. 2020 19(4):730-743. PMID: 33451705.
• Storey AJ, Hardman RE, Byrum SD, [et al., including Edmondson RD]. Accurate and Sensitive Quantitation of the Dynamic Heat Shock Proteome Using Tandem Mass Tags. Journal of proteome research. 2020 19(3):1183-1195. PMID: 32027144. PMCID: PMC7241437.
• Larsen CP, Sharma SG, Caza TN, [et al., including Edmondson RD]. Serum amyloid P deposition is a sensitive and specific feature of membranous-like glomerulopathy with masked IgG kappa deposits. Kidney international. 2020 97(3):602-608. PMID: 32001064. PMCID: PMC7869973.
• Ramirez AM, Byrum SD, Beenken KE, [et al., including Edmondson RD]. Exploiting Correlations between Protein Abundance and the Functional Status of saeRS and sarA To Identify Virulence Factors of Potential Importance in the Pathogenesis of Staphylococcus aureus Osteomyelitis. ACS infectious diseases. 2020 6(2):237-249. PMID: 31722523. PMCID: PMC7294808.
• Ren Z, Ahn JH, Liu H, [et al., including Edmondson RD]. PHF19 promotes multiple myeloma tumorigenicity through PRC2 activation and broad H3K27me3 domain formation. Blood. 2019 134(14):1176-1189. PMID: 31383640. PMCID: PMC6776795.
• Shields BD, Koss B, Taylor EM, [et al., including Edmondson R]. Loss of E-Cadherin Inhibits CD103 Antitumor Activity and Reduces Checkpoint Blockade Responsiveness in Melanoma. Cancer research. 2019 79(6):1113-1123. PMID: 30674537. PMCID: PMC6420873.
• West KL, Byrum SD, Mackintosh SG, [et al., including Edmondson RD]. Proteomic characterization of the arsenic response locus in S. cerevisiae. Epigenetics. 2019 14(2):130-145. PMID: 30739529. PMCID: PMC6557609.
• Zybailov BL, Glazko GV, Rahmatallah Y, [et al., including Edmondson RD]. Metaproteomics reveals potential mechanisms by which dietary resistant starch supplementation attenuates chronic kidney disease progression in rats. PloS one. 2019 14(1):e0199274. PMID: 30699108. PMCID: PMC6353070.
• Byrum SD, Loughran AJ, Beenken KE, [et al., including Edmondson RD]. Label-Free Proteomic Approach to Characterize Protease-Dependent and -Independent Effects of sarA Inactivation on the Staphylococcus aureus Exoproteome. Journal of proteome research. 2018 17(10):3384-3395. PMID: 30209945. PMCID: PMC6209314.
• Zangari M, Yoo H, Shin I, [et al., including Edmondson R]. Thymic PTH Increases After Thyroparathyroidectomy in C57BL/KaLwRij Mice. Endocrinology. 2018 159(4):1561-1569. PMID: 29381784. PMCID: PMC5839736.
• Arthur JM, Tackett A, Karakala N, Edmondson RD. Proteomic Analysis for Identification of Biomarkers that Predict Severe Acute Kidney Injury. Nephron. 2018 140(2):129-133. PMID: 29990988. PMCID: PMC6398162.
• Shields BD, Mahmoud F, Taylor EM, [et al., including Edmondson RD]. Indicators of responsiveness to immune checkpoint inhibitors. Scientific reports. 2017 7(1):807. PMID: 28400597. PMCID: PMC5429745.