Ricky D Edmondson, PhD

Research Program: Cancer Biology Faculty Rank: Professor Campus: University of Arkansas for Medical Sciences College: College of Medicine Department: Biochem & Molecular Histone Epigenet

Cancer Research Interest

• Type of Research: Basic

Contact Information

• Email Address: RDEDMONDSON@UAMS.EDU
• Profiles Research Networking Software: View Profile

Active Grants

• NIH/Nat. Inst. of General Medical Sciences – 1R01GM141040
  “Discovery and Characterization of Novel Sepsis Proteome Biomarkers”
  Co-Investigator
  9/10/2021 – 8/31/2025

Recent Publications

• Zhao S, Lu J, Pan B, [et al., including Edmondson RD]. TNRC18 engages H3K9me3 to mediate silencing of endogenous retrotransposons. Nature. 2023 623(7987):633-642. PMID: 37938770. PMCID: PMC11000523.
• Garg S, Morehead LC, Bird JT, [et al., including Edmondson RD]. Characterization of methionine dependence in melanoma cells. Molecular omics. 2023. PMID: 37782107. PMCID: PMC10903584.
• Caza TN, Storey AJ, Hassen SI, [et al., including Edmondson RD]. Discovery of seven novel putative antigens in membranous nephropathy and membranous lupus nephritis identified by mass spectrometry. Kidney international. 2023. PMID: 36638888. PMCID: PMC9974866.
• Das BK, Wang L, Fujiwara T, [et al., including Edmondson R]. Transferrin receptor 1-mediated iron uptake regulates bone mass in mice via osteoclast mitochondria and cytoskeleton. eLife. 2022 11. PMID: 35758636. PMCID: PMC9352353.
• Li D, Yu X, Kottur J, [et al., including Edmondson RD]. Discovery of a dual WDR5 and Ikaros PROTAC degrader as an anti-cancer therapeutic. Oncogene. 2022. PMID: 35525905. PMCID: PMC9189076.
• Xu C, Meng F, Park KS, [et al., including Edmondson RD]. A NSD3-targeted PROTAC suppresses NSD3 and cMyc oncogenic nodes in cancer cells. Cell chemical biology. 2021. PMID: 34469831. PMCID: PMC8882712.
• Caza TN, Hassen SI, Kenan DJ, [et al., including Edmondson RD]. Transforming Growth Factor Beta Receptor 3 (TGFBR3)-Associated Membranous Nephropathy. Kidney360. 2021 2(8):1275-1286. PMID: 35369660. PMCID: PMC8676385.
• Ahn JH, Davis ES, Daugird TA, [et al., including Edmondson RD]. Phase separation drives aberrant chromatin looping and cancer development. Nature. 2021. PMID: 34163069. PMCID: PMC8647409.
• Fan H, Guo Y, Tsai YH, [et al., including Edmondson RD]. A conserved BAH module within mammalian BAHD1 connects H3K27me3 to Polycomb gene silencing. Nucleic acids research. 2021 49(8):4441-4455. PMID: 33823544. PMCID: PMC8096256.
• Al-Rabadi LF, Caza T, Trivin-Avillach C, [et al., including Edmondson R]. Serine Protease HTRA1 as a Novel Target Antigen in Primary Membranous Nephropathy. Journal of the American Society of Nephrology : JASN. 2021. PMID: 33952630. PMCID: PMC8425645.
• Xu C, Tsai YH, Galbo PM, [et al., including Edmondson RD]. Cistrome analysis of YY1 uncovers a regulatory axis of YY1:BRD2/4-PFKP during tumorigenesis of advanced prostate cancer. Nucleic acids research. 2021. PMID: 33849067. PMCID: PMC8136773.
• Li J, Galbo PM Jr, Gong W, [et al., including Edmondson RD]. ZMYND11-MBTD1 induces leukemogenesis through hijacking NuA4/TIP60 acetyltransferase complex and a PWWP-mediated chromatin association mechanism. Nature communications. 2021 12(1):1045. PMID: 33594072. PMCID: PMC7886901.
• Caza TN, Hassen SI, Kuperman M, [et al., including Edmondson R]. Neural cell adhesion molecule 1 is a novel autoantigen in membranous lupus nephritis. Kidney international. 2020. PMID: 33045259. PMCID: PMC8032825.
• Koss B, Boerma M, Shields BD, [et al., including Edmondson RD]. Epigenetic Control of Cdkn2a.Arf Protects Tumor-Infiltrating Lymphocytes from Metabolic Exhaustion. Cancer research. 2020. PMID: 33004350. PMCID: PMC7642172.
• Caza T, Hassen S, Dvanajscak Z, [et al., including Edmondson R]. NELL1 is a target antigen in malignancy-associated membranous nephropathy. Kidney international. 2020. PMID: 32828756. PMCID: PMC7895854.
• Storey AJ, Naceanceno KS, Lan RS, [et al., including Edmondson RD]. ProteoViz: a tool for the analysis and interactive visualization of phosphoproteomics data. Molecular omics. 2020. PMID: 32347222. PMCID: PMC7423749.
• Chua XY, Mensah T, Aballo T, [et al., including Edmondson RD]. Tandem Mass Tag Approach Utilizing Pervanadate BOOST Channels Delivers Deeper Quantitative Characterization of the Tyrosine Phosphoproteome. Molecular & cellular proteomics : MCP. 2020 19(4):730-743. PMID: 32071147. PMCID: PMC7124467.
• Chua XY, Mensah T, Aballo T, [et al., including Edmondson RD]. Tandem Mass Tag Approach Utilizing Pervanadate BOOST Channels Delivers Deeper Quantitative Characterization of the Tyrosine Phosphoproteome. Molecular & cellular proteomics : MCP. 2020 19(4):730-743. PMID: 33451705.
• Storey AJ, Hardman RE, Byrum SD, [et al., including Edmondson RD]. Accurate and Sensitive Quantitation of the Dynamic Heat Shock Proteome Using Tandem Mass Tags. Journal of proteome research. 2020 19(3):1183-1195. PMID: 32027144. PMCID: PMC7241437.
• Larsen CP, Sharma SG, Caza TN, [et al., including Edmondson RD]. Serum amyloid P deposition is a sensitive and specific feature of membranous-like glomerulopathy with masked IgG kappa deposits. Kidney international. 2020 97(3):602-608. PMID: 32001064. PMCID: PMC7869973.
• Ramirez AM, Byrum SD, Beenken KE, [et al., including Edmondson RD]. Exploiting Correlations between Protein Abundance and the Functional Status of saeRS and sarA To Identify Virulence Factors of Potential Importance in the Pathogenesis of Staphylococcus aureus Osteomyelitis. ACS infectious diseases. 2020 6(2):237-249. PMID: 31722523. PMCID: PMC7294808.