Hongjiang Si, PhD

Full Member

Research Program:

Cancer Biology

Faculty Rank:

Assistant Professor

Campus:

University of Arkansas for Medical Sciences

College:

College of Medicine

Department:

Radiation Oncology

Cancer Research Interest

Disease Site Focus: Breast
Research Focus Area: Treatment
Type of Research: Translational
Research Keywords: Breast Cancer, Wnt signaling, Ca2+ signaling, Tumor microenvironment, Metastasis, Drug resistance
Research Interest Statement: My research trajectory has been focused on understanding complex signaling pathways in development and disease. My current research focuses on the cellular and molecular mechanisms of Wnt/calcium signaling in mammary gland development, breast cancer metastasis, and therapeutic resistance. By integrating mouse models, organoid systems, advanced imaging, and single-cell/spatial transcriptomics, I aim to uncover novel therapeutic targets in breast and related cancers. My long-term research program is dedicated to deciphering this mechanism and identifying novel therapeutic vulnerabilities within the Wnt/calcium signaling network in cancers.