Mokarram Hossain, PhD

Full Member

Research Program:

Cancer Therapeutics

Faculty Rank:

Assistant Professor

Campus:

University of Arkansas for Medical Sciences

College:

College of Pharmacy

Department:

Pharmaceutical Science

Cancer Research Interest

Disease Site Focus: Breast, GI, Head and Neck, No Specific Disease Site
Research Focus Area: Treatment
Type of Research: Basic, Translational
Research Keywords: Bispecific immune engager, Immunotherapy, Cancer immunology.
Research Interest Statement: My laboratory investigates how myeloid immune cells contribute to the growth and metastasis of solid cancers, and how they can be reprogrammed into tumor-killing cells using bispecific antibodies. In addition, we are developing bispecific immune engagers specifically designed to target solid tumors with limited treatment options.

NIH/Nat. Center for Advancing Translational Sciences – K12TR004924
“Novel Immunotherapy for Pancreatic Cancer: Extracellular Matrix-Targeting Myeloid Engaged; Mentor: Alan Tackett, PhD)”
Principal Investigator
7/1/2025 – 6/30/2027

Hossain M, Huang J, Su Y, [et al.]. SUMOylation Protects Endothelial Cell-Expressed Leukocyte-Specific Protein 1 from Ubiquitination-Mediated Proteasomal Degradation and Facilitates Its Nuclear Export. International journal of molecular sciences. 2026 27(2). PMID: 41596753.
Hossain M, Shim R, Lee WY, [et al.]. Gata6(+) resident peritoneal macrophages promote the growth of liver metastasis. Nature communications. 2022 13(1):4406. PMID: 35906202.