Mokarram Hossain, PhD

Full Member

Research Program:

Cancer Therapeutics

Faculty Rank:

Assistant Professor

Campus:

University of Arkansas for Medical Sciences

College:

College of Pharmacy

Department:

Pharmaceutical Science

Cancer Research Interest

Disease Site Focus: Breast, GI, Head and Neck, No Specific Disease Site
Research Focus Area: Treatment
Type of Research: Basic, Translational
Research Keywords: Bispecific immune engager, Immunotherapy, Cancer immunology.
Research Interest Statement: My laboratory investigates how myeloid immune cells contribute to the growth and metastasis of solid cancers, and how they can be reprogrammed into tumor-killing cells using bispecific antibodies. In addition, we are developing bispecific immune engagers specifically designed to target solid tumors with limited treatment options.

Hossain M, Shim R, Lee WY, [et al.]. Gata6(+) resident peritoneal macrophages promote the growth of liver metastasis. Nature communications. 2022 13(1):4406. PMID: 35906202.
Zindel J, Peiseler M, Hossain M, [et al.]. Primordial GATA6 macrophages function as extravascular platelets in sterile injury. Science (New York, N.Y.). 2021 371(6533). PMID: 33674464.