Joey Beard
Affiliate- Trainee Member
|
| Research Program:
Cancer Biology
Faculty Rank:
Graduate Assistant
Campus:
University of Arkansas for Medical Sciences
Department:
Biochemistry & Molecular Biology
|
Cancer Research Interest
- Disease Site Focus: No Specific Disease Site
- Research Focus Area: Carcinogenesis
- Type of Research: Basic
- Research Keywords: Carcinogenesis, Genome maintenance, DNA repair, DNA replication
- Research Interest Statement: Helicases broadly function to unwind double-stranded DNA or RNA structures. DNA helicases “unpack” genetic information, enabling the replication, repair, and transcription machineries to access our genome, which is crucial for genome maintenance. We are studying the role of DNA Helicase B in these processes, and my project will characterize the role of other proteins that interact with DNA Helicase B, which will provide insights into how DNA Helicase B aids genome maintenance and impacts cell cycle progression. This is especially important because dysfunctional genome maintenance and faulty cell cycle regulation have been linked to cancer development and affect cellular aging.
Contact Information
- Email Address: JSBeard@uams.edu
Recent Publications
- Osei B, May BH, Beard JS, [et al.]. Rare SNP in the HELB gene interferes with RPA interaction and cellular function of HELB. NAR molecular medicine. 2025 2(2):ugaf019. PMID: 40496644. PMCID: PMC12147029.
- Beard JS, Francis LK, Forrest RC, [et al.]. Trapping of yFACT at 3' ends of genes is not a universal characteristic of yeast versions of Bryant-Li-Bhoj syndrome histone H3 mutants. microPublication biology. 2024 2024. PMID: 39525290. PMCID: PMC11544422.