Santanu Samanta, MD

Research Program: Cancer Therapeutics Faculty Rank: Assistant Professor Campus: University of Arkansas for Medical Sciences College: College of Medicine Department: Radiation Oncology

Cancer Research Interest

• Disease Site Focus: Head and Neck, Gynecology
• Research Focus Area: Treatment
• Type of Research: Clinical
• Research Interest Statement: Dr. Samanta is radiation oncologist and assistant professor at the University of Arkansas for Medical Sciences. Dr. Samanta joined the UAMS team after completing a residency in Radiation Oncology at the University of Maryland, and Maryland Proton Treatment Center. Prior to this residency training, he also completed a residency training in radiation oncology at CMC Vellore, India one of the premium medical institutions in India. During his residency training at Maryland he received the outstanding clinical research award and also the Radiological Society of North America (RSNA) award for his outstanding research. Dr Samanta joined as faculty and assistant professor at the University of Arkansas for Medical Sciences. He is also the director of radiation oncology at the UAMS Baptist North Little joint venture clinic. He is also one of the ‘Proton lead’ physician in the group and his responsibilities involve reviewing proton appropriate cases, reviewing proton radiation plans and overview proton work flow. He also leads the Gyn brachytherapy services and has expanded the brachytherapy treatment using the new state of art HYBRID brachytherapy devices for gynecological cancer. This brachytherapy program now receives referral for complex and interstitial treatment from providers across the entire state of Arkansas. Dr Samanta is also assistant Program Director for radiation Oncology medical residency program and works very closely with residents for their education and training as well as for overall program growth and recruitment process. He also received the ARRO educator award in 2023 for mentoring residents in the department. Dr Samanta has also participated in various research projects that has led to multiple posters, oral abstracts as well peer reviewed publications. He was also invited for multiple lectures on his expertise in proton therapy for head and neck cancer.

Contact Information

• Email Address: SSAMANTA@UAMS.EDU
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Open Clinical Trials

• “TRANSPARENT: Single-Arm Study of Toripalimab in Combination with Cisplatin and Gemcitabine in Recurrent Metastatic Nasopharyngeal Carcinoma Systemic Treatment Naïve Participants” (NCT06457503)
• “Daily Adaptive External Beam Radiation Therapy in the Treatment of Carcinoma of the Cervix: A Prospective Trial of an Individualized Approach for Intestinal Toxicity Reduction (ARTIA-Cervix)” (NCT05197881)
• “Using Virtual Reality Technology to Improve Patient Experience and Quality of Care during Brachytherapy” (NCT05440760)

Recent Publications

• Slater NN, Farsi S, Rogers AL, [et al., including Samanta S]. Reirradiation in head and neck squamous cell carcinoma; prognostic indicators, oncologic and functional outcomes. American journal of otolaryngology. 2024 45(6):104482. PMID: 39116720.
• Megahed R, Prabhu AV, Mack DP, [et al., including Samanta S]. Re-irradiation of recurrent head and neck cancers using pulsed reduced dose rate radiotherapy: An institutional series. Oral oncology. 2024 152:106778. PMID: 38555751.
• Nichols M, Kesaria A, Spencer HJ, [et al., including Samanta S]. Opioid Use in Patients With Cervical Cancer at a Tertiary Academic Medical Center. Anticancer research. 2024 44(1):151-155. PMID: 38160002.
• Prabhu AV, Peterman M, Kesaria A, [et al., including Samanta S]. Virtual reality technology: A potential tool to enhance brachytherapy training and delivery. Brachytherapy. 2023 22(6):709-715. PMID: 37679242.
• Kerans SJ, Samanta S, Vyfhuis MAL, [et al.]. Racial Analysis of Clinical and Biochemical Outcomes in Patients With Prostate Cancer Treated With Low-Dose-Rate Brachytherapy. International journal of radiation oncology, biology, physics. 2023 116(1):87-95. PMID: 36336224.
• Alkhaldi H, Goloubeva O, Rapoport AP, [et al., including Samanta S]. Outcomes of Busulfan, Fludarabine, and 400 cGy Total Body Irradiation Compared With Busulfan and Fludarabine Reduced-Intensity Conditioning Regimens for Allogeneic Stem Cell Transplantation in Adult Patients With Hematologic Diseases: A Single-Center Experience. Transplantation proceedings. 2023 55(1):214-224. PMID: 36635141.
• Leiser D, Samanta S, Strauss J, [et al.]. Correction: Role of caveolin-1 as a biomarker for radiation resistance and tumor aggression in lung cancer. PloS one. 2022 17(5):e0268256. PMID: 35503800. PMCID: PMC9064073.
• Lutfi F, Holtzman NG, Kansagra AJ, [et al., including Samanta S]. The impact of bridging therapy prior to CD19-directed chimeric antigen receptor T-cell therapy in patients with large B-cell lymphoma. British journal of haematology. 2021 195(3):405-412. PMID: 34500492.
• Leiser D, Samanta S, Eley J, [et al.]. Role of caveolin-1 as a biomarker for radiation resistance and tumor aggression in lung cancer. PloS one. 2021 16(11):e0258951. PMID: 34762666. PMCID: PMC8584669.
• Remick JS, Kowalski E, Samanta S, [et al.]. Health-Related Quality of Life and Patient-Reported Outcomes in Radiation Oncology Clinical Trials. Current treatment options in oncology. 2020 21(11):87. PMID: 32862317.
• Mahmood J, Alexander AA, Samanta S, [et al.]. A Combination of Radiotherapy, Hyperthermia, and Immunotherapy Inhibits Pancreatic Tumor Growth and Prolongs the Survival of Mice. Cancers. 2020 12(4). PMID: 32326142. PMCID: PMC7226594.