Visanu Wanchai, PhD

Research Program: Cancer Biology Faculty Rank: Posdoctoral researcher Campus: University of Arkansas for Medical Sciences College: College of Medicine Department: Biomedical Informatics

Cancer Research Interest

• Disease Site Focus: Multiple Myeloma
• Research Focus Area: Informatics
• Type of Research: Translational
• Research Keywords: Bioinformatics, Biomedical Informatics, Cancer Genomics, Multiple Myeloma
• Research Interest Statement: My research interest is to develop cutting-edge tools and techniques for big data analysis in multi-omics that can be used in a broad range of biomedical applications, and investigate key genes and regulatory elements involved in cancer. The insights from my research will provide higher coverage and greater resolution of the dynamic nature of cancer cells throughout disease progression. It can also be used to track disease progression and improve the diagnosis and treatment of cancer.

Contact Information

• Email Address: VWANCHAI@UAMS.EDU
• Profiles Research Networking Software: View Profile

Recent Publications

• Cheng Y, Sun F, Alapat DV, [et al., including Wanchai V]. Multi-omics reveal immune microenvironment alterations in multiple myeloma and its precursor stages. Blood cancer journal. 2024 14(1):194. PMID: 39505839. PMCID: PMC11541562.
• Guo W, Strouse C, Mery D, [et al., including Wanchai V]. A Risk Stratification System in Myeloma Patients with Autologous Stem Cell Transplantation. Cancers. 2024 16(6). PMID: 38539451. PMCID: PMC10969019.
• Nookaew I, Xiong J, Onal M, [et al., including Wanchai V]. Refining the identity of mesenchymal cell types associated with murine periosteal and endosteal bone. The Journal of biological chemistry. 2024 300(4):107158. PMID: 38479598. PMCID: PMC11007436.
• Sun F, Cheng Y, Wanchai V, [et al.]. Bispecific BCMA/CD24 CAR-T cells control multiple myeloma growth. Nature communications. 2024 15(1):615. PMID: 38242888. PMCID: PMC10798961.
• Wassenaar TM, Harville T, Chastain J, [et al., including Wanchai V]. DNA structural features and variability of complete MHC locus sequences. Frontiers in bioinformatics. 2024 4:1392613. PMID: 39022183. PMCID: PMC11251971.
• Sun F, Cheng Y, Chen JR, [et al., including Wanchai V]. BCMA- and CST6-specific CAR T cells lyse multiple myeloma cells and suppress murine osteolytic lesions. The Journal of clinical investigation. 2023. PMID: 37883186. PMCID: PMC10760955.
• Cheng Y, Sun F, Alapat DV, [et al., including Wanchai V]. High NEK2 expression in myeloid progenitors suppresses T cell immunity in multiple myeloma. Cell reports. Medicine. 2023 4(10):101214. PMID: 37794587. PMCID: PMC10591052.
• Sun F, Cheng Y, Ying J, [et al., including Wanchai V]. A gene signature can predict risk of MGUS progressing to multiple myeloma. Journal of hematology & oncology. 2023 16(1):70. PMID: 37386588. PMCID: PMC10308756.
• Wassenaar TM, Wanchai V, Ussery DW. Comparison of Monkeypox virus genomes from the 2017 Nigeria outbreak and the 2022 outbreak. Journal of applied microbiology. 2022 133(6):3690-3698. PMID: 36074056. PMCID: PMC9828465.
• Wanchai V, Jenjaroenpun P, Leangapichart T, [et al.]. CReSIL: accurate identification of extrachromosomal circular DNA from long-read sequences. Briefings in bioinformatics. 2022. PMID: 36198068. PMCID: PMC10144670.
• Wassenaar TM, Wanchai V, Buzard G, Ussery DW. The first three waves of the Covid-19 pandemic hint at a limited genetic repertoire for SARS-CoV-2. FEMS microbiology reviews. 2022 46(3). PMID: 35076068. PMCID: PMC9075578.
• Wadley T, Moon SH, DeMott MS, [et al., including Wanchai V]. Nanopore Sequencing for Detection and Characterization of Phosphorothioate Modifications in Native DNA Sequences. Frontiers in microbiology. 2022 13:871937. PMID: 35531280. PMCID: PMC9069010.
• Wongsurawat T, Jenjaroenpun P, Wanchai V, Nookaew I. Native RNA or cDNA Sequencing for Transcriptomic Analysis: A Case Study on Saccharomyces cerevisiae. Frontiers in bioengineering and biotechnology. 2022 10:842299. PMID: 35497361. PMCID: PMC9039254.
• Abram K, Udaondo Z, Bleker C, [et al., including Wanchai V]. Mash-based analyses of Escherichia coli genomes reveal 14 distinct phylogroups. Communications biology. 2021 4(1):117. PMID: 33500552. PMCID: PMC7838162.
• Jenjaroenpun P, Wanchai V, Ono-Moore KD, [et al.]. Two SARS-CoV-2 Genome Sequences of Isolates from Rural U.S. Patients Harboring the D614G Mutation, Obtained Using Nanopore Sequencing. Microbiology resource announcements. 2020 10(1). PMID: 33334896. PMCID: PMC8407695.
• Jenjaroenpun P, Wongsurawat T, Wadley TD, [et al., including Wanchai V]. Decoding the epitranscriptional landscape from native RNA sequences. Nucleic acids research. 2020. PMID: 32710622. PMCID: PMC7826254.
• Wanchai V, Nookaew I, Ussery DW. ProdMX: Rapid query and analysis of protein functional domain based on compressed sparse matrices. Computational and structural biotechnology journal. 2020 18:3890-3896. PMID: 33335686. PMCID: PMC7719867.