Sydnye Leigh Shuttleworth, MD, PhD
Affiliate Member
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| Research Program:
Cancer Biology
Faculty Rank:
MD/PhD Student
Campus:
University of Arkansas for Medical Sciences
College:
College of Medicine
Department:
Biochemistry & Molecular Biology
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Cancer Research Interest
- Disease Site Focus: No Specific Disease Site
- Research Focus Area: Treatment
- Type of Research: Basic
- Research Keywords: Cellular Therapies, Proteomics, Proteome Turnover
- Research Interest Statement: My research interests primarily include studying T cell biology in the context of solid tumors and in the engineering of cellular therapies. I am employing proteomic approaches to understand proteome turnover dynamics in T cells and how it may impact the ability of a T cell to function inside the hostile microenvironment of solid tumors.
Contact Information
- Email Address: SLSHUTTLEWORTH@UAMS.EDU
Recent Publications
- McCrury M, Swafford K, Shuttleworth SL, [et al.]. Bifunctional inhibitor reveals NEK2 as a therapeutic target and regulator of oncogenic pathways in lymphoma. Molecular cancer therapeutics. 2023. PMID: 37816504. PMCID: PMC10932871.
- Hansa RK, Khan MMK, Frangie MM, [et al., including Shuttleworth SL]. 4-4-(Anilinomethyl)-3-[4-(trifluoromethyl)phenyl]-1H-pyrazol-1-ylbenzoic acid derivatives as potent anti-gram-positive bacterial agents. European journal of medicinal chemistry. 2021 219:113402. PMID: 33845234. PMCID: PMC8165011.