Sindhu Janarthanam Malapati, MD

Research Program: Cancer Prevention and Population Sciences Faculty Rank: Assistant Professor Campus: University of Arkansas for Medical Sciences College: College of Medicine Department: Internal Medicine

Cancer Research Interest

• Disease Site Focus: Breast
• Research Focus Area: Treatment
• Type of Research: Clinical
• Research Keywords: De-escalation, Symptom management
• Research Interest Statement: De-escalation trials in breast cancer, symptom management, survivorship in young women with breast cancer, financial toxicity and disparities research.

Contact Information

• Email Address: SMALAPATI@UAMS.EDU
• Profiles Research Networking Software: View Profile

Open Clinical Trials

• “S1703 RANDOMIZED NON-INFERIORITY TRIAL COMPARING OVERALL SURVIVAL OF PATIENTS MONITORED WITH SERUM TUMOR MARKER DIRECTED DISEASE MONITORING (STMDDM) VERSUS USUAL CARE IN PATIENTS WITH METASTATIC HORMONE RECEPTOR POSITIVE HER-2 NEGATIVE BREAST CANCER” (NCT03723928)
• “A Phase III, Randomized, Open-Label, Multicenter Study Evaluating the Efficacy and Safety of Giredestrant Plus Everolimus Compared with the Physician’s choice of Endocrine Therapy Exemestane Plus Everolimus in Patients with Estrogen Receptor-Positive, HER2-Negative, Locally Advanced or Metastatic Breast Cancer” (NCT05306340)

Active Grants

• American Cancer Society, Inc. – RSGI-23-1039245-01-HOPS
  “Affordable care act on racial disparity in endocrine therapy use among females with early stage hormone receptor positive breast cancer”
  Co-Investigator
  07/01/23 – 06/30/25

Publications

• Tu SM, Trikannad AK, Vellanki S, [et al., including Malapati S]. Stem Cell Origin of Cancer: Clinical Implications beyond Immunotherapy for Drug versus Therapy Development in Cancer Care. Cancers. 2024 16(6). PMID: 38539487. PMCID: PMC10969562.
• Park YM, Jung W, Yeo Y, [et al., including Malapati SJ]. Mid- and long-term risk of atrial fibrillation among breast cancer surgery survivors. BMC medicine. 2024 22(1):88. PMID: 38419017. PMCID: PMC10903065.
• Malapati SJ, Idossa D, Singh SRK, [et al.]. Parent Penalty: Parental Leave Experiences of Trainees and Early-Career Faculty in Oncology Subspecialties. JCO oncology practice. 2023 19(10):899-906. PMID: 37708434.
• Li C, Malapati SJ, Guire JT, Hutchins LF. Consistency Between State's Cancer Registry and All-Payer Claims Database in Documented Radiation Therapy Among Patients Who Received Breast Conservative Surgery. JCO clinical cancer informatics. 2023 7:e2200099. PMID: 36724402. PMCID: PMC10166563.
• Tu SM, Singh SR, Arnaoutakis K, [et al., including Malapati S]. Stem Cell Theory of Cancer: Implications for Translational Research from Bedside to Bench. Cancers. 2022 14(14). PMID: 35884406. PMCID: PMC9321703.
• Malapati S, Singh SRK, Kumar R, Hadid T. Outcomes of in-hospital cardiopulmonary resuscitation for cardiac arrest in adult patients with metastatic solid cancers: A Nationwide Inpatient Sample database analysis from 2012 to 2014. Cancer. 2021 127(12):2148-2157. PMID: 33687740.
• Singh SRK, Malapati SJ, Kumar R, [et al.]. NCDB Analysis of Melanoma 2004-2015: Epidemiology and Outcomes by Subtype, Sociodemographic Factors Impacting Clinical Presentation, and Real-World Survival Benefit of Immunotherapy Approval. Cancers. 2021 13(6). PMID: 33810182. PMCID: PMC8004999.
• Kumar R, Castillero F, Bhandari S, [et al., including Malapati S]. The Hispanic Paradox in Non-Small Cell Lung Cancer. Hematology/oncology and stem cell therapy. 2021. PMID: 33775613.
• Kumar R, Bhandari S, Singh SRK, [et al., including Malapati S]. Incidence and outcomes of heparin-induced thrombocytopenia in solid malignancy: an analysis of the National Inpatient Sample Database. British journal of haematology. 2020 189(3):543-550. PMID: 31990984.
• Zayed Y, Kheiri B, Barbarawi M, [et al., including Malapati S]. Extended duration of thromboprophylaxis for medically ill patients: a systematic review and meta-analysis of randomised controlled trials. Internal medicine journal. 2020 50(2):192-199. PMID: 31276276.