Yong-Moon Mark Park, MD, MS, PhD

Research Program: Cancer Prevention and Population Sciences Faculty Rank: Assistant Professor Campus: University of Arkansas for Medical Sciences College: College of Public Health Department: Epidemiology

Cancer Research Interest

• Disease Site Focus: Breast
• Research Focus Area: Prevention, Diagnosis/ Prognosis, Informatics, Health Disparities, Treatment
• Type of Research: Population Sciences
• Research Keywords: breast cancer, nutrition and diet, epidemiology, cardiometabolic dysfunction , prevention, environmental factors , cancer survivors
• Research Interest Statement: My research program focuses on etiology and prevention of breast and other cancers and addresses the influence of dietary and environmental factors and cardiometabolic dysfunction on risk and prognosis of cancer. My work also considers mechanisms by which dietary patterns and nutrients affect cancer risk. Furthermore, I am interested in cardiometabolic complications and prognosis following diagnosis and treatment of cancer. Ultimately, I hope that my research will provide insight into strategies for effective prevention and intervention of breast and other cancers, as well as cardiometabolic dysfunction in cancer survivors.

Contact Information

• Email Address: YPARK@UAMS.EDU
• Profiles Research Networking Software: View Profile

Active Grants

• NIH/Nat. Inst. of Environmental Health Sciences – 1U24ES037082
  “Promoting scientific and workforce diversity by enriching the Arkansas Rural Community Health Study (ARCH) among Mother-Daughter Pairs”
  Co-Investigator
  12/19/2024 – 11/30/2029
• State of Arkansas – AWD00056260
  “Enhancing Prediction of Cardiovascular Toxicity in Breast Cancer Survivors: A Comprehensive Machine Learning Approach Integrating Comorbidity Networks”
  Principal Investigator
  9/1/2024 – 8/31/2026
• NIH/Nat. Heart, Lung & Blood Institute – 1K01HL175206
  “Understanding disparities in cardiovascular toxicity among breast cancer survivors in Arkansas”
  Principal Investigator
  8/23/2024 – 7/31/2028

Recent Publications

• Kim SH, Park GE, Bertrand KA, [et al., including Park YM]. Mammographic density as a predictor of invasive breast cancer and ductal carcinoma in situ in over six million South Korean women. Breast cancer research and treatment. 2025. PMID: 40019668.
• Jung W, Park YM, Park SH, [et al.]. Novel Breast Cancer Risk Assessment Tools for Pre- and Post-Menopausal Asian Women: Development and Validation in a Nationwide Mammographic Screening Cohort. Cancer research and treatment. 2025. PMID: 39901701.
• Ellis ET, Young SG, Carroll R, [et al., including Park YM]. Carcinogenic air pollutants and breast cancer risk in the Arkansas rural community health study: A nested case-control study. Environmental pollution (Barking, Essex : 1987). 2025 368:125709. PMID: 39828205.
• Jung W, Park YM, Yu J, [et al.]. Weight Changes and Heart Failure Risk After Breast Cancer Development. JAMA oncology. 2025. PMID: 39786741. PMCID: PMC11926620.
• Jung W, Park SH, Park YM, [et al.]. Weight change and cardiovascular disease incidence in breast cancer survivors: a nationwide cohort study. Breast cancer research and treatment. 2025. PMID: 39762706.
• Cheon DY, Park YM, Park MS, [et al.]. Depression and risk of stroke and mortality after percutaneous coronary intervention: A nationwide population study. Journal of internal medicine. 2024 296(6):468-480. PMID: 39370680.
• Jung W, Cho IY, Jung J, [et al., including Park YM]. Changes in Physical Activity and Cardiovascular Disease Risk in Cancer Survivors: A Nationwide Cohort Study. JACC. CardioOncology. 2024 6(6):879-889. PMID: 39801643. PMCID: PMC11711819.
• Koo HY, Cho IY, Um YJ, [et al., including Park YM]. Risk of Diabetes Mellitus in Adults with Intellectual Disabilities: A Nationwide Cohort Study. Endocrinology and metabolism (Seoul, Korea). 2024. PMID: 39566545. PMCID: PMC11898312.
• Cho IY, Koo HY, Um YJ, [et al., including Park YM]. Intellectual disabilities and risk of cardiovascular diseases: A population-based cohort study. Disability and health journal. 2024:101754. PMID: 39562242.
• Park KY, Huh Y, Nam GE, [et al., including Park YM]. Changes in physical activity and all-cause mortality among individuals with dementia: a cohort study using the National Health Insurance Service Database in Korea. British journal of sports medicine. 2024 58(21):1258-1266. PMID: 39472033.
• Yun JS, Han K, Kim B, [et al., including Park YM]. All-cause and cause-specific mortality risks in individuals with diabetes living alone: A large-scale population-based cohort study. Diabetes research and clinical practice. 2024 217:111876. PMID: 39343144.
• Li C, Peng C, DelNero P, [et al., including Park YM]. Investigating the coverage of the Arkansas All-Payer Claims Database for examining health disparities related to persistent poverty areas in colorectal cancer patients. Cancer causes & control : CCC. 2024. PMID: 39306812.
• Baek JH, Zhu Y, Jackson CL, Park YM. Artificial Light at Night and Type 2 Diabetes Mellitus. Diabetes & metabolism journal. 2024 48(5):847-863. PMID: 39313230. PMCID: PMC11449813.
• Park YM, Amick Iii BC, McElfish PA, [et al.]. Income dynamics and risk of colorectal cancer in individuals with type 2 diabetes: a nationwide population-based cohort study. Journal of epidemiology. 2024. PMID: 38972733. PMCID: PMC11637811.
• Park YM, Baek JH, Lee HS, [et al.]. Income variability and incident cardiovascular disease in diabetes: a population-based cohort study. European heart journal. 2024 45(21):1920-1933. PMID: 38666368.
• Jung W, Cho IY, Jung J, [et al., including Park YM]. Association between physical activity changes and risk of incident ischemic stroke following cancer diagnosis: A nationwide retrospective cohort study. Cancer. 2024. PMID: 38723109.
• Jung W, Cho IY, Jung J, [et al., including Park YM]. Changes in physical activity and diabetes risk after cancer diagnosis: a nationwide cohort study. Journal of cancer survivorship : research and practice. 2024. PMID: 38647592.
• Park YM, Jung W, Yeo Y, [et al.]. Mid- and long-term risk of atrial fibrillation among breast cancer surgery survivors. BMC medicine. 2024 22(1):88. PMID: 38419017. PMCID: PMC10903065.
• Von Holle A, Shi M, O'Brien KM, [et al., including Park YM]. Association between two common SNPs, rs6564851 and rs6420424, and lutein and zeaxanthin levels in a cohort of US postmenopausal women with a family history of breast cancer. Frontiers in nutrition. 2024 11:1372393. PMID: 39534433. PMCID: PMC11554543.
• Crawford B, Steck SE, Sandler DP, [et al., including Park YM]. Association between healthy dietary patterns and markers of oxidative stress in the Sister Study. European journal of nutrition. 2023. PMID: 38070016.
• Liu J, Lavie CJ, Park YM, Bagiella E. Geographic variation and trends in prevalence of obesity among US adolescents, 2016-2021. Public health. 2023 223:128-130. PMID: 37634452.
• Crawford B, Steck SE, Sandler DP, [et al., including Park YM]. Dietary patterns, socioeconomic disparities, and risk of type 2 diabetes in the Sister Study. Diabetes research and clinical practice. 2023 204:110906. PMID: 37708977. PMCID: PMC10624134.
• Ko SH, Han KD, Park YM, [et al.]. Diabetes Mellitus in the Elderly Adults in Korea: Based on Data from the Korea National Health and Nutrition Examination Survey 2019 to 2020. Diabetes & metabolism journal. 2023 47(5):643-652. PMID: 37549924. PMCID: PMC10555543.
• Park D, Park YM, Ko SH, [et al.]. Association of general and central obesity, and their changes with risk of knee osteoarthritis: a nationwide population-based cohort study. Scientific reports. 2023 13(1):3796. PMID: 36882508. PMCID: PMC9992488.
• Park D, Park YM, Ko SH, [et al.]. Association between knee osteoarthritis and the risk of cardiovascular disease and the synergistic adverse effects of lack of exercise. Scientific reports. 2023 13(1):2777. PMID: 36797339. PMCID: PMC9935498.
• Baek JH, Park YM, Han KD, [et al.]. Comparison of Operational Definition of Type 2 Diabetes Mellitus Based on Data from Korean National Health Insurance Service and Korea National Health and Nutrition Examination Survey. Diabetes & metabolism journal. 2023. PMID: 36750233. PMCID: PMC10040628.
• Choi MK, Park YM, Shivappa N, [et al.]. Inflammatory potential of diet and risk of mortality in normal-weight adults with central obesity. Clinical nutrition (Edinburgh, Scotland). 2023 42(2):208-215. PMID: 36603461. PMCID: PMC10284332.
• Han K, Yoo J, Yeo Y, [et al., including Park YM]. Association Between Metabolic Syndrome and Risk of Esophageal Cancer: a Nationwide Population-Based Study. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 2022. PMID: 36166509.
• Yun JS, Han K, Park YM, [et al.]. Adherence to healthy lifestyle behaviors as a preventable risk factor for severe hypoglycemia in people with type 2 diabetes: A longitudinal nationwide cohort study. Journal of diabetes investigation. 2022. PMID: 35474300. PMCID: PMC9943249.
• Lee OH, Park YM, Ko SH, [et al.]. Synergistic association between underweight and type 2 diabetes on the development of laryngeal cancer: a national population-based retrospective cohort study. BMC cancer. 2022 22(1):345. PMID: 35351050. PMCID: PMC8966305.
• Park YM, Lilyquist J, Van't Erve TJ, [et al.]. Association of dietary and plasma carotenoids with urinary F(2)-isoprostanes. European journal of nutrition. 2022. PMID: 35253072. PMCID: PMC9283284.
• Han K, Yoo J, Yeo Y, [et al., including Park YM]. Association of Metabolic Parameter Variability with Esophageal Cancer Risk: A Nationwide Population-Based Study. Journal of personalized medicine. 2022 12(3). PMID: 35330375. PMCID: PMC8950346.
• Kang HS, Park YM, Ko SH, [et al.]. Impaired Lung Function and Lung Cancer Incidence: A Nationwide Population-Based Cohort Study. Journal of clinical medicine. 2022 11(4). PMID: 35207361. PMCID: PMC8880094.
• Diaz-Santana MV, O'Brien KM, Park YM, [et al.]. Persistence of Risk for Type 2 Diabetes After Gestational Diabetes Mellitus. Diabetes care. 2022. PMID: 35104325. PMCID: PMC9016728.
• Kang S, Park YM, Kwon DJ, [et al.]. Reproductive Life Span and Severe Hypoglycemia Risk in Postmenopausal Women with Type 2 Diabetes Mellitus. Diabetes & metabolism journal. 2022. PMID: 35067011. PMCID: PMC9353572.
• Zheng J, Zhu T, Yang G, [et al., including Park YM]. The Isocaloric Substitution of Plant-Based and Animal-Based Protein in Relation to Aging-Related Health Outcomes: A Systematic Review. Nutrients. 2022 14(2). PMID: 35057453. PMCID: PMC8781188.
• Kim SH, Park YM, Han K, [et al.]. Association of weight change following smoking cessation with the risk of tuberculosis development: A nationwide population-based cohort study. PloS one. 2022 17(4):e0266262. PMID: 35390038. PMCID: PMC8989195.
• Huh G, Han KD, Park YM, [et al.]. Comorbidities associated with high-risk obstructive sleep apnea based on the STOP-BANG questionnaire: a nationwide population-based study. The Korean journal of internal medicine. 2022 38(1):80-92. PMID: 36353789. PMCID: PMC9816691.
• Choi YH, Park YM, Hur KJ, [et al.]. Duration of diabetes mellitus and risk of kidney and bladder cancer: a longitudinal nationwide cohort study. American journal of cancer research. 2022 12(8):4050-4061. PMID: 36119837. PMCID: PMC9441993.
• Lunyera J, Park YM, Ward JB, [et al.]. A prospective study of multiple sleep dimensions and hypertension risk among white, black and Hispanic/Latina women: findings from the Sister Study. Journal of hypertension. 2021 39(11):2210-2219. PMID: 34620810. PMCID: PMC8501231.
• Kresovich JK, Park YM, Keller JA, [et al.]. Healthy eating patterns and epigenetic measures of biological age. The American journal of clinical nutrition. 2021. PMID: 34637497. PMCID: PMC8754996.
• Ahn S, Han K, Jeun SS, [et al., including Park YM]. Associations of General and Abdominal Obesity with the Risk of Glioma Development. Cancers. 2021 13(12). PMID: 34201103. PMCID: PMC8228893.
• Park YM, Sandler DP. Making sense of associations between type 2 diabetes, metformin, and breast cancer risk. British journal of cancer. 2021. PMID: 33911196. PMCID: PMC8476566.
• Cho Y, Han K, Kim DH, [et al., including Park YM]. Cumulative Exposure to Metabolic Syndrome Components and the Risk of Dementia: A Nationwide Population-Based Study. Endocrinology and metabolism (Seoul, Korea). 2021 36(2):424-435. PMID: 33849249. PMCID: PMC8090478.
• Park YM, Shivappa N, Petimar J, [et al.]. Dietary inflammatory potential, oxidative balance score, and risk of breast cancer: Findings from the Sister Study. International journal of cancer. 2021. PMID: 33783833. PMCID: PMC8256885.
• Jayanama K, Theou O, Godin J, [et al., including Park YM]. Relationship between diet quality scores and the risk of frailty and mortality in adults across a wide age spectrum. BMC medicine. 2021 19(1):64. PMID: 33722232. PMCID: PMC7962372.
• Pes GM, Park YM, Sechi GP. Cholesterol Trafficking in the Brain: Are We Overlooking an Important Risk Factor for Parkinson Disease?. Neurology. 2021 96(10):465-466. PMID: 33536270.
• Choi IY, Chun S, Shin DW, [et al., including Park YM]. Changes in Metabolic Syndrome Status and Breast Cancer Risk: A Nationwide Cohort Study. Cancers. 2021 13(5). PMID: 33803268. PMCID: PMC7967214.
• Hwang S, Park YM, Han KD, [et al.]. Associations of general obesity and central obesity with the risk of hepatocellular carcinoma in a Korean population: A national population-based cohort study. International journal of cancer. 2021 148(5):1144-1154. PMID: 32955731.
• Park YM, Bookwalter DB, O'Brien KM, [et al.]. A prospective study of type 2 diabetes, metformin use, and risk of breast cancer. Annals of oncology : official journal of the European Society for Medical Oncology. 2021 32(3):351-359. PMID: 33516778. PMCID: PMC7995619.
• Yun JS, Park YM, Han K, [et al.]. Severe hypoglycemia and the risk of end stage renal disease in type 2 diabetes. Scientific reports. 2021 11(1):4305. PMID: 33619302. PMCID: PMC7900096.
• Ko YM, Ko SH, Han K, [et al., including Park YM]. Importance of Awareness and Treatment for Diabetes in Influenza Vaccination Coverage of Diabetic Patients under 65 Years: A Population-Based Study. Diabetes & metabolism journal. 2021 45(1):55-66. PMID: 32602274. PMCID: PMC7850874.
• Park JW, Han K, Shin DW, [et al., including Park YM]. Obesity and breast cancer risk for pre- and postmenopausal women among over 6 million Korean women. Breast cancer research and treatment. 2021 185(2):495-506. PMID: 33010023.
• Kim JY, Park YM, Lee GN, [et al.]. Association between toothbrushing and non-alcoholic fatty liver disease. PloS one. 2021 16(5):e0243686. PMID: 34043630. PMCID: PMC8158973.
• Ahn S, Han K, Jeun SS, [et al., including Park YM]. Association between height and the risk of primary brain malignancy in adults: a nationwide population-based cohort study. Neuro-oncology advances. 2021 3(1):vdab098. PMID: 34738083. PMCID: PMC8562729.
• Lee EY, Han K, Kim DH, [et al., including Park YM]. Exposure-weighted scoring for metabolic syndrome and the risk of myocardial infarction and stroke: a nationwide population-based study. Cardiovascular diabetology. 2020 19(1):153. PMID: 32993664. PMCID: PMC7525999.
• Kim YS, Park YM, Han KD, [et al.]. Fasting glucose level and all-cause or cause-specific mortality in Korean adults: a nationwide cohort study. The Korean journal of internal medicine. 2020. PMID: 32623847. PMCID: PMC8137392.
• Ahn S, Han KD, Park YM, [et al.]. Cigarette Smoking Is Associated with Increased Risk of Malignant Gliomas: A Nationwide Population-Based Cohort Study. Cancers. 2020 12(5). PMID: 32466105. PMCID: PMC7280985.
• Lo JJ, Park YM, Sinha R, Sandler DP. Association between meat consumption and risk of breast cancer: Findings from the Sister Study. International journal of cancer. 2020 146(8):2156-2165. PMID: 31389007. PMCID: PMC7002279.