Disease Site Focus:
Thoracic/ Lung, Multiple Myeloma, Head and Neck, Gynecology, GI, Breast, Cutaneous/Melanoma
Research Focus Area:
Informatics, Prevention, Treatment
Microbiome, Metagenomics, Microbiome Data Science, Microbiomics, Molecular Biology, Microbial Ecology, Phylogenetics, Phylogenomics
Type of Research:
Research Interest Statement:
I am a microbiome scientist that have been continually involved in the development of microbiome data science and bioinformatics tools such as QIIME 2, PyCogent, PanFP, and RESCRIPt along with continuing code contributions to existing open-source microbiome data science tools. I have also served as a microbiome science and bioinformatics consultant for several academic, national, and private-sector research laboratories. There has been ever-increasing interest in how the microbiome can affect the progression, and therapeutic treatment of cancer. Over the last several years there have been numerous publications that investigated the relationship of microbiota and a variety of cancers such as colon, lung, pancreatic, ovarian, and many more. In fact, the cancer microbiome is of great interest to the National Cancer Institute (NCI), which has specifically called out ?Investigating the Role of Microbiomes in Cancer? in their 2020 Annual Plan & Budget Proposal and was further outlined in their ?Bugs as Cancer Drugs? commentary which was subsequently followed by the announcement of two NIH-NCI RFAs. In this vein, I am currently collaborating with the following UAMS researcher?s various cancer-related projects: I am working with 1) Dr. Ruud Dings to characterize the responses of the gut microbiome to antibiotic-induced perturbation and their association to the tumor microenvironment; 2) Dr. Mayumi Nakagawa on elucidating the relationships and responses of the cervicovaginal, oral, and gut microbial communities to the presence of human papillomaviruses; 3) Dr. Antiu00f1o Allen on associations of the microbiome to chemotherapeutic treatments and murine behavior.
“Improvement of cellular immunotherapy during dysbi”
09/15/21 – 08/31/26
NIH/Nat. Cancer Institute – 2R01CA143130
“Understanding and Enhancing T-Cell Responses to High Risk Human Papillomaviruses-Renewal”
07/01/21 – 06/30/26
Ippolito JR, Piccolo BD, Robeson MS, [et al.]. Iron deficient diets modify the gut microbiome and reduce the severity of enteric infection in a mouse model of S. Typhimurium-induced enterocolitis. The Journal of nutritional biochemistry. 2022 107:109065. PMID: 35609848.
Elolimy A, Rosa F, Tripp P, [et al., including Robeson MS]. Bacterial and Fungal Adaptations in Cecum and Distal Colon of Piglets Fed With Dairy-Based Milk Formula in Comparison With Human Milk. Frontiers in microbiology. 2022 13:801854. PMID: 35401465. PMCID: PMC8989072.
Robeson MS 2nd, Manna K, Randolph C, [et al.]. Short-Term Metformin Treatment Enriches Bacteroides dorei in an Obese Liver Steatosis Zucker Rat Model. Frontiers in microbiology. 2022 13:834776. PMID: 35432282. PMCID: PMC9006818.
Piccolo BD, Graham JL, Kang P, [et al., including Robeson MS]. Progression of diabetes is associated with changes in the ileal transcriptome and ileal-colon morphology in the UC Davis Type 2 Diabetes Mellitus rat. Physiological reports. 2021 9(22):e15102. PMID: 34806320. PMCID: PMC8606862.
Carper DL, Weston DJ, Barde A, [et al., including Robeson MS 2nd]. Cultivating the Bacterial Microbiota of Populus Roots. mSystems. 2021 6(3):e0130620. PMID: 34156297.
Dillon MR, Bolyen E, Adamov A, [et al., including Robeson M]. Experiences and lessons learned from two virtual, hands-on microbiome bioinformatics workshops. PLoS computational biology. 2021 17(6):e1009056. PMID: 34166363.
Abram K, Udaondo Z, Bleker C, [et al., including Robeson MS 2nd]. Mash-based analyses of Escherichia coli genomes reveal 14 distinct phylogroups. Communications biology. 2021 4(1):117. PMID: 33500552. PMCID: PMC7838162.
Shibata T, Nakagawa M, Coleman HN, [et al., including Robeson MS 2nd]. Evaluation of DNA extraction protocols from liquid-based cytology specimens for studying cervical microbiota. PloS one. 2021 16(8):e0237556. PMID: 34460815. PMCID: PMC8404996.
Sallinger E, Robeson MS, Haselkorn TS. Characterization of the bacterial microbiomes of social amoebae and exploration of the roles of host and environment on microbiome composition. Environmental microbiology. 2021 23(1):126-142. PMID: 33063404.
Graw S, Tackett A, Chappell K, [et al., including Robeson MS 2nd]. Multi-omics data integration considerations and study design for biological systems and disease. Molecular omics. 2020. PMID: 33347526.
Kandel S, Sripiboon S, Jenjaroenpun P, [et al., including Robeson MS 2nd]. 16S rRNA Gene Amplicon Profiling of Baby and Adult Captive Elephants in Thailand. Microbiology resource announcements. 2020 9(24). PMID: 32527771. PMCID: PMC7291096.
Darcy JL, Washburne AD, Robeson MS, [et al.]. A phylogenetic model for the recruitment of species into microbial communities and application to studies of the human microbiome. The ISME journal. 2020 14(6):1359-1368. PMID: 32076128. PMCID: PMC7242462.
Smyser TJ, Tabak MA, Slootmaker C, [et al., including Robeson MS 2nd]. Mixed ancestry from wild and domestic lineages contributes to the rapid expansion of invasive feral swine. Molecular ecology. 2020 29(6):1103-1119. PMID: 32080922.
Wassenaar TM, Jun SR, Robeson M, Ussery DW. Comparative genomics of hepatitis A virus, hepatitis C virus, and hepatitis E virus provides insights into the evolutionary history of Hepatovirus species. MicrobiologyOpen. 2020 9(2):e973. PMID: 31742930. PMCID: PMC7002107.
Bokulich NA, Ziemski M, Robeson MS 2nd, Kaehler BD. Measuring the microbiome: Best practices for developing and benchmarking microbiomics methods. Computational and structural biotechnology journal. 2020 18:4048-4062. PMID: 33363701. PMCID: PMC7744638.
Jenkins SV, Robeson MS 2nd, Griffin RJ, [et al.]. Gastrointestinal Tract Dysbiosis Enhances Distal Tumor Progression through Suppression of Leukocyte Trafficking. Cancer research. 2019 79(23):5999-6009. PMID: 31591154. PMCID: PMC6891208.
Alkam D, Jenjaroenpun P, Wongsurawat T, [et al., including Robeson M]. Genomic characterization of mumps viruses from a large-scale mumps outbreak in Arkansas, 2016. Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases. 2019 75:103965. PMID: 31319177. PMCID: PMC6832845.
Bolyen E, Rideout JR, Dillon MR, [et al., including Robeson MS 2nd]. Author Correction: Reproducible, interactive, scalable and extensible microbiome data science using QIIME 2. Nature biotechnology. 2019 37(9):1091. PMID: 31399723.
Bolyen E, Rideout JR, Dillon MR, [et al., including Robeson MS 2nd]. Reproducible, interactive, scalable and extensible microbiome data science using QIIME 2. Nature biotechnology. 2019 37(8):852-857. PMID: 31341288. PMCID: PMC7015180.
Ravilla R, Coleman HN, Chow CE, [et al., including Robeson MS]. Cervical Microbiome and Response to a Human Papillomavirus Therapeutic Vaccine for Treating High-Grade Cervical Squamous Intraepithelial Lesion. Integrative cancer therapies. 2019 18:1534735419893063. PMID: 31833799. PMCID: PMC6913049.
Kennedy RC, Fling RR, Robeson MS, [et al.]. Temporal dynamics of gut microbiota in triclocarban-exposed weaned rats. Environmental science and pollution research international. 2018 25(15):14743-14751. PMID: 29536423.
Knelman JE, Graham EB, Prevéy JS, [et al., including Robeson MS]. Interspecific Plant Interactions Reflected in Soil Bacterial Community Structure and Nitrogen Cycling in Primary Succession. Frontiers in microbiology. 2018 9:128. PMID: 29467741. PMCID: PMC5808232.
Robeson MS 2nd, Khanipov K, Golovko G, [et al.]. Assessing the utility of metabarcoding for diet analyses of the omnivorous wild pig (Sus scrofa). Ecology and evolution. 2018 8(1):185-196. PMID: 29321862. PMCID: PMC5756863.
Andrei A?, Baricz A, Robeson MS 2nd, [et al.]. Hypersaline sapropels act as hotspots for microbial dark matter. Scientific reports. 2017 7(1):6150. PMID: 28733590. PMCID: PMC5522462.
King AJ, Preheim SP, Bailey KL, [et al., including Robeson MS 2nd]. Temporal Dynamics of In-Field Bioreactor Populations Reflect the Groundwater System and Respond Predictably to Perturbation. Environmental science & technology. 2017 51(5):2879-2889. PMID: 28112946.
Kennedy RC, Fling RR, Robeson MS, [et al.]. Temporal Development of Gut Microbiota in Triclocarban Exposed Pregnant and Neonatal Rats. Scientific reports. 2016 6:33430. PMID: 27646684. PMCID: PMC5028839.
Utturkar SM, Cude WN, Robeson MS Jr, [et al.]. Enrichment of Root Endophytic Bacteria from Populus deltoides and Single-Cell-Genomics Analysis. Applied and environmental microbiology. 2016 82(18):5698-708. PMID: 27422831. PMCID: PMC5007785.
Andrei A?, Robeson MS 2nd, Baricz A, [et al.]. Contrasting taxonomic stratification of microbial communities in two hypersaline meromictic lakes. The ISME journal. 2015 9(12):2642-56. PMID: 25932617. PMCID: PMC4817630.
Jun SR, Robeson MS, Hauser LJ, [et al.]. PanFP: pangenome-based functional profiles for microbial communities. BMC research notes. 2015 8:479. PMID: 26409790. PMCID: PMC4584126.