Disease Site Focus:
Cutaneous/Melanoma, Multiple Myeloma
Research Focus Area:
Diagnosis/ Prognosis, Informatics
Type of Research:
Research Interest Statement:
I am interested in applying cutting edge proteomics techniques to facilitate biomarker studies for a variety of cancer types. The field of proteomics has rapidly matured in recent years, allowing for deep, high-throughput studies of clinical samples. My goal is to work with physician scientists and apply these techniques to solve current problems in today's clinical practice.
Li D, Yu X, Kottur J, [et al., including Storey AJ]. Discovery of a dual WDR5 and Ikaros PROTAC degrader as an anti-cancer therapeutic. Oncogene. 2022. PMID: 35525905.
Morelle J, Caza T, Debiec H, [et al., including Storey A]. Cubilin and amnionless protein are novel target antigens in anti-brush border antibody disease. Kidney international. 2022. PMID: 35276203.
Delgado M, Washam CL, Urbaniak A, [et al., including Storey AJ]. Phosphoproteomics Provides Novel Insights into the Response of Primary Acute Lymphoblastic Leukemia Cells to Microtubule Depolymerization in G1 Phase of the Cell Cycle. ACS omega. 2021 6(38):24949-24959. PMID: 34604676. PMCID: PMC8482483.
Waldrip ZJ, Burdine L, Harrison DK, [et al., including Storey AJ]. DNA-PKcs kinase activity stabilizes the transcription factor Egr1 in activated immune cells. The Journal of biological chemistry. 2021:101209. PMID: 34562454.
Xu C, Meng F, Park KS, [et al., including Storey AJ]. A NSD3-targeted PROTAC suppresses NSD3 and cMyc oncogenic nodes in cancer cells. Cell chemical biology. 2021. PMID: 34469831.
Ahn JH, Davis ES, Daugird TA, [et al., including Storey AJ]. Phase separation drives aberrant chromatin looping and cancer development. Nature. 2021. PMID: 34163069.
Chappell K, Graw S, Washam CL, [et al., including Storey AJ]. PTMViz: a tool for analyzing and visualizing histone post translational modification data. BMC bioinformatics. 2021 22(1):275. PMID: 34039258. PMCID: PMC8157737.
Fan H, Guo Y, Tsai YH, [et al., including Storey AJ]. A conserved BAH module within mammalian BAHD1 connects H3K27me3 to Polycomb gene silencing. Nucleic acids research. 2021 49(8):4441-4455. PMID: 33823544. PMCID: PMC8096256.
Al-Rabadi LF, Caza T, Trivin-Avillach C, [et al., including Storey A]. Serine Protease HTRA1 as a Novel Target Antigen in Primary Membranous Nephropathy. Journal of the American Society of Nephrology : JASN. 2021. PMID: 33952630.
Xu C, Tsai YH, Galbo PM, [et al., including Storey AJ]. Cistrome analysis of YY1 uncovers a regulatory axis of YY1:BRD2/4-PFKP during tumorigenesis of advanced prostate cancer. Nucleic acids research. 2021. PMID: 33849067.
Li J, Galbo PM Jr, Gong W, [et al., including Storey AJ]. ZMYND11-MBTD1 induces leukemogenesis through hijacking NuA4/TIP60 acetyltransferase complex and a PWWP-mediated chromatin association mechanism. Nature communications. 2021 12(1):1045. PMID: 33594072.
Caza TN, Hassen SI, Kuperman M, [et al., including Storey A]. Neural cell adhesion molecule 1 is a novel autoantigen in membranous lupus nephritis. Kidney international. 2020. PMID: 33045259. PMCID: PMC8032825.
Koss B, Boerma M, Shields BD, [et al., including Storey AJ]. Epigenetic Control of Cdkn2a.Arf Protects Tumor-Infiltrating Lymphocytes from Metabolic Exhaustion. Cancer research. 2020. PMID: 33004350.
Caza T, Hassen S, Dvanajscak Z, [et al., including Storey A]. NELL1 is a target antigen in malignancy-associated membranous nephropathy. Kidney international. 2020. PMID: 32828756.
Storey AJ, Naceanceno KS, Lan RS, [et al.]. ProteoViz: a tool for the analysis and interactive visualization of phosphoproteomics data. Molecular omics. 2020. PMID: 32347222.
Storey AJ, Hardman RE, Byrum SD, [et al.]. Accurate and Sensitive Quantitation of the Dynamic Heat Shock Proteome Using Tandem Mass Tags. Journal of proteome research. 2020 19(3):1183-1195. PMID: 32027144. PMCID: PMC7241437.
Larsen CP, Sharma SG, Caza TN, [et al., including Storey AJ]. Serum amyloid P deposition is a sensitive and specific feature of membranous-like glomerulopathy with masked IgG kappa deposits. Kidney international. 2020 97(3):602-608. PMID: 32001064.
Storey AJ, Wang HP, Protacio RU, [et al.]. Targeted Forward Genetics: Population-Scale Analyses of Allele Replacements Spanning Thousands of Base Pairs in Fission Yeast. G3 (Bethesda, Md.). 2019 9(12):4097-4106. PMID: 31597677. PMCID: PMC6893178.
Ren Z, Ahn JH, Liu H, [et al., including Storey AJ]. PHF19 promotes multiple myeloma tumorigenicity through PRC2 activation and broad H3K27me3 domain formation. Blood. 2019 134(14):1176-1189. PMID: 31383640. PMCID: PMC6776795.
Chiang TC, Koss B, Su L, [et al., including Storey A]. Effect of Sulforaphane and 5-Aza-2'-Deoxycytidine on Melanoma Cell Growth. Medicines (Basel, Switzerland). 2019 6(3). PMID: 31252639. PMCID: PMC6789461.
Shields BD, Koss B, Taylor EM, [et al., including Storey AJ]. Loss of E-Cadherin Inhibits CD103 Antitumor Activity and Reduces Checkpoint Blockade Responsiveness in Melanoma. Cancer research. 2019 79(6):1113-1123. PMID: 30674537. PMCID: PMC6420873.
Storey AJ, Wang HP, Protacio RU, [et al.]. Chromatin-mediated regulators of meiotic recombination revealed by proteomics of a recombination hotspot. Epigenetics & chromatin. 2018 11(1):64. PMID: 30373637. PMCID: PMC6205778.
Byrum SD, Loughran AJ, Beenken KE, [et al., including Storey AJ]. Label-Free Proteomic Approach to Characterize Protease-Dependent and -Independent Effects of sarA Inactivation on the Staphylococcus aureus Exoproteome. Journal of proteome research. 2018 17(10):3384-3395. PMID: 30209945. PMCID: PMC6209314.
Kriss CL, Gregory-Lott E, Storey AJ, [et al.]. In Vivo Metabolic Tracing Demonstrates the Site-Specific Contribution of Hepatic Ethanol Metabolism to Histone Acetylation. Alcoholism, clinical and experimental research. 2018 42(10):1909-1923. PMID: 30030934. PMCID: PMC6208134.