Horacio Gomez-Acevedo, PhD

Research Program: Cancer Therapeutics Faculty Rank: Associate Professor Campus: University of Arkansas for Medical Sciences College: College of Medicine Department: Biomedical Informatics

Cancer Research Interest

• Disease Site Focus: Breast, Thoracic/ Lung
• Research Focus Area: Informatics
• Type of Research: Basic
• Research Keywords: Imaging informatics, Cancer genomics, data integration
• Research Interest Statement: My research interest lies in the data mining of different “omics” modalities and their integration to better understand the cancer progression mostly for breast and lung cancer. Whereas most of my present and past research has been focused in genomics, the integration of genetic and imaging data is my main research area of interest. I want to take advantage of The Cancer Imaging Archive hosted at UAMS to integrate genomics and radiomics with state-of-the-art computational methodologies that will improve and ultimately guide treatments for the benefit cancer patients in Arkansas.

Contact Information

• Email Address: GOMEZACEVEDOHORACIO@UAMS.EDU
• Profiles Research Networking Software: View Profile

Active Grants

• Centers for Disease Control & Prevention – 1 U01 DD001306-01-00
  “Birth Defects Study to Evaluate Pregnancy exposureS (BD-STEPS) Core– Arkansas Center”
  Co-Investigator
  09/01/23 – 03/31/27

Publications

• Palmieri M, Joseph TE, O'Brien CA, [et al., including Gomez-Acevedo H]. Retraction notice to "Deletion of the scavenger receptor Scarb1 in myeloid cells does not affect bone mass" [Bone 170(2023) 116702]. Bone. 2023 176:116885. PMID: 37633107. PMCID: PMC10805070.
• Palmieri M, Joseph TE, O'Brien CA, [et al., including Gomez-Acevedo H]. Deletion of the scavenger receptor Scarb1 in myeloid cells does not affect bone mass. Bone. 2023 170:116702. PMID: 36773885. PMCID: PMC10040251.
• Dimori M, Pokrovskaya ID, Liu S, [et al., including Gomez-Acevedo H]. A Rab33b missense mouse model for Smith-McCort dysplasia shows bone resorption defects and altered protein glycosylation. Frontiers in genetics. 2023 14:1204296. PMID: 37359363. PMCID: PMC10285484.
• Palmieri M, Joseph TE, O'Brien CA, [et al., including Gomez-Acevedo H]. Retraction: Deletion of the scavenger receptor Scarb1 in osteoblast progenitors does not affect bone mass. PloS one. 2023 18(8):e0290458. PMID: 37585400. PMCID: PMC10431598.
• Ponte F, Kim HN, Warren A, [et al., including Gomez-Acevedo H]. Mmp13 deletion in mesenchymal cells increases bone mass and may attenuate the cortical bone loss caused by estrogen deficiency. Scientific reports. 2022 12(1):10257. PMID: 35715555. PMCID: PMC9205908.
• Ronis MJJ, Gomez-Acevedo H, Shankar K, [et al.]. Soy Formula Is Not Estrogenic and Does Not Result in Reproductive Toxicity in Male Piglets: Results from a Controlled Feeding Study. Nutrients. 2022 14(5). PMID: 35268101. PMCID: PMC8912539.
• Palmieri M, Joseph TE, O'Brien CA, [et al., including Gomez-Acevedo H]. Deletion of the scavenger receptor Scarb1 in osteoblast progenitors does not affect bone mass. PloS one. 2022 17(3):e0265893. PMID: 35349600. PMCID: PMC8963559.
• Palmieri M, Almeida M, Nookaew I, [et al., including Gomez-Acevedo H]. Neutralization of oxidized phospholipids attenuates age-associated bone loss in mice. Aging cell. 2021 20(8):e13442. PMID: 34278710. PMCID: PMC8373359.
• Palmieri M, Kim HN, Gomez-Acevedo H, [et al.]. A Neutralizing Antibody Targeting Oxidized Phospholipids Promotes Bone Anabolism in Chow-Fed Young Adult Mice. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 2020. PMID: 32990984. PMCID: PMC7855899.
• Gomez-Acevedo H, Dai Y, Strub G, [et al.]. Identification of putative biomarkers for Infantile Hemangiomas and Propranolol treatment via data integration. Scientific reports. 2020 10(1):3261. PMID: 32094357. PMCID: PMC7039967.
• Gomez-Acevedo H, Patterson JD, Sardar S, [et al.]. SMARC-B1 deficient sinonasal carcinoma metastasis to the brain with next generation sequencing data: a case report of perineural invasion progressing to leptomeningeal invasion. BMC cancer. 2019 19(1):827. PMID: 31438887. PMCID: PMC6704572.