Se-Ran Jun, PhD

Research Program: Cancer Therapeutics Faculty Rank: Assistant Professor Campus: University of Arkansas for Medical Sciences College: College of Medicine Department: Biomedical Informatics

Cancer Research Interest

• Research Interest Statement: I am a bioinformatician. I am interested in genomic epidemiology of antimicrobial resistance and microbiome-targeted intervention for cancer infection and cancer therapy. My research laboratory focuses on real-time genomic surveillance of antimicrobial resistance dealing with big data, EHR data, machine learning, visualization, and further multi-omics integration using Oxford Nanopore Technologies.

Contact Information

• Email Address: SJUN@UAMS.EDU
• Profiles Research Networking Software: View Profile

Active Grants

• National Science Foundation – OIA-1946391
  “Data Governance in Pathogen Surveillance”
  Principal Investigator
  04/01/23 – 03/30/25
• National Institute of Food and Agriculture – 2022-69015-36720
  “Assessment of antibiotic resistance in fresh veget”
  Co-Investigator
  08/01/22 – 07/31/25
• National Science Foundation – OIA-1946391
  “Robust and Trusted Data Analytics”
  Co-Investigator
  07/01/22 – 08/31/23
• NIH/Nat. Inst. of Allergy & Infectious Diseases – 1R21AI169138
  “Real-Time High Resolution Method for Genomic Surve”
  Principal Investigator
  05/10/22 – 04/30/24
• NIH/Nat. Inst. of Allergy & Infectious Diseases – 1R03AI164158
  “In vivo essential genome of Salmonella”
  Principal Investigator
  08/18/21 – 07/31/23
• NIH/Nat. Inst. of Allergy & Infectious Diseases – 2U19AI067773
  “Development of a fast and sensitive biodosimetry a”
  Co-Investigator
  05/01/21 – 07/31/23

Publications

• Udaondo Z, Abram K, Kothari A, Jun SR. Top-Down Genomic Surveillance Approach To Investigate the Genomic Epidemiology and Antibiotic Resistance Patterns of Enterococcus faecium Detected in Cancer Patients in Arkansas. Microbiology spectrum. 2023:e0490122. PMID: 36995227.
• Udaondo Z, Abram KZ, Gulley T, [et al., including Jun SR]. Complete Genome Sequence of a Non-Carbapenemase-Producing Carbapenem-Resistant Providencia rettgeri Strain Isolated from a Clinical Urine Sample in Arkansas. Microbiology resource announcements. 2022 11(8):e0047422. PMID: 35894621. PMCID: PMC9387286.
• Udaondo Z, Abram KZ, Kothari A, Jun SR. Insertion sequences and other mobile elements associated with antibiotic resistance genes in Enterococcus isolates from an inpatient with prolonged bacteraemia. Microbial genomics. 2022 8(8). PMID: 35921144. PMCID: PMC9484755.
• Moon SH, Udaondo Z, Jun SR, Huang E. Cefiderocol heteroresistance in Klebsiella pneumoniae is linked to mutations in the siderophore receptor cirA and ?-lactamase activities. International journal of antimicrobial agents. 2022:106635. PMID: 35820535.
• Heo S, Shin MS, Lee MO, [et al., including Jun SR]. Factors Related to Patients' Self-care and Self-care Confidence in Korean Patients With Heart Failure and Their Caregivers: A Cross-sectional, Correlational Study. The Journal of cardiovascular nursing. 2022. PMID: 35507026.
• Moon SH, Udaondo Z, Abram KZ, [et al., including Jun SR]. Isolation of AmpC- and extended spectrum ?-lactamase-producing Enterobacterales from fresh vegetables in the United States. Food control. 2022 132. PMID: 34629764. PMCID: PMC8494183.
• Abram KZ, Jun SR, Udaondo Z. Pseudomonas aeruginosa Pangenome: Core and Accessory Genes of a Highly Resourceful Opportunistic Pathogen. Advances in experimental medicine and biology. 2022 1386:3-28. PMID: 36258067.
• Jun SR, Boerma M, Udaondo Z, [et al.]. Plasma Metabolomics in a Nonhuman Primate Model of Abdominal Radiation Exposure. Metabolites. 2021 11(8). PMID: 34436481. PMCID: PMC8398377.
• Moon SH, Udaondo Z, Li X, [et al., including Jun SR]. Isolation and characterisation of carbapenemase-producing and polymyxin B-resistant Enterobacter bugandensis from a vegetable. Journal of global antimicrobial resistance. 2021 26:264-265. PMID: 34329791. PMCID: PMC8647156.
• Bose C, Alves I, Singh P, [et al., including Jun SR]. Sulforaphane prevents age-associated cardiac and muscular dysfunction through Nrf2 signaling. Aging cell. 2020 19(11):e13261. PMID: 33067900. PMCID: PMC7681049.
• Jun SR, Cheema A, Bose C, [et al.]. Multi-Omic Analysis Reveals Different Effects of Sulforaphane on the Microbiome and Metabolome in Old Compared to Young Mice. Microorganisms. 2020 8(10). PMID: 33003447. PMCID: PMC7599699.
• Udaondo Z, Jenjaroenpun P, Wongsurawat T, [et al., including Jun SR]. Two Cases of Vancomycin-Resistant Enterococcus faecium Bacteremia With Development of Daptomycin-Resistant Phenotype and its Detection Using Oxford Nanopore Sequencing. Open forum infectious diseases. 2020 7(6):ofaa180. PMID: 32550237. PMCID: PMC7291683.
• Jenjaroenpun P, Wongsurawat T, Udaondo Z, [et al., including Jun SR]. Complete Genome Sequences of Four Isolates of Vancomycin-Resistant Enterococcus faecium with the vanA Gene and Two Daptomycin Resistance Mutations, Obtained from Two Inpatients with Prolonged Bacteremia. Microbiology resource announcements. 2020 9(6). PMID: 32029568. PMCID: PMC7005116.
• Wassenaar TM, Jun SR, Robeson M, Ussery DW. Comparative genomics of hepatitis A virus, hepatitis C virus, and hepatitis E virus provides insights into the evolutionary history of Hepatovirus species. MicrobiologyOpen. 2020 9(2):e973. PMID: 31742930. PMCID: PMC7002107.
• Adhikari B, Jun SR, Kwon YM, [et al.]. Effects of Housing Types on Cecal Microbiota of Two Different Strains of Laying Hens During the Late Production Phase. Frontiers in veterinary science. 2020 7:331. PMID: 32656252. PMCID: PMC7324799.
• Pornputtapong N, Acheampong DA, Patumcharoenpol P, [et al., including Jun SR]. KITSUNE: A Tool for Identifying Empirically Optimal K-mer Length for Alignment-Free Phylogenomic Analysis. Frontiers in bioengineering and biotechnology. 2020 8:556413. PMID: 33072720. PMCID: PMC7538862.
• Alkam D, Jenjaroenpun P, Wongsurawat T, [et al., including Jun SR]. Genomic characterization of mumps viruses from a large-scale mumps outbreak in Arkansas, 2016. Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases. 2019 75:103965. PMID: 31319177. PMCID: PMC6832845.
• Udaondo Z, Wongsurawat T, Jenjaroenpun P, [et al., including Jun SR]. Draft Genome Sequences of 48 Vancomycin-Resistant Enterococcus faecium Strains Isolated from Inpatients with Bacteremia and Urinary Tract Infection. Microbiology resource announcements. 2019 8(15). PMID: 30975810. PMCID: PMC6460033.
• Jenkins SV, Vang KB, Gies A, [et al., including Jun SR]. Sample storage conditions induce post-collection biases in microbiome profiles. BMC microbiology. 2018 18(1):227. PMID: 30591021. PMCID: PMC6307155.
• Cabal A, Jun SR, Jenjaroenpun P, [et al.]. Genome-Based Comparison of Clostridioides difficile: Average Amino Acid Identity Analysis of Core Genomes. Microbial ecology. 2018 76(3):801-813. PMID: 29445826. PMCID: PMC6132499.
• Wongsurawat T, Athipanyasilp N, Jenjaroenpun P, [et al., including Jun SR]. Case of Microcephaly after Congenital Infection with Asian Lineage Zika Virus, Thailand. Emerging infectious diseases. 2018 24(9). PMID: 29985788. PMCID: PMC6106416.
• Timm CM, Carter KR, Carrell AA, [et al., including Jun SR]. Abiotic Stresses Shift Belowground Populus-Associated Bacteria Toward a Core Stress Microbiome. mSystems. 2018 3(1). PMID: 29404422. PMCID: PMC5781258.
• Jun SR, Wassenaar TM, Wanchai V, [et al.]. Suggested mechanisms for Zika virus causing microcephaly: what do the genomes tell us?. BMC bioinformatics. 2017 18(Suppl 14):471. PMID: 29297281. PMCID: PMC5751795.
• Alkam D, Wongsurawat T, Jenjaroenpun P, [et al., including Jun SR]. Three Complete Genome Sequences of Genotype G Mumps Virus from the 2016 Outbreak in Arkansas, USA. Genome announcements. 2017 5(32). PMID: 28798162. PMCID: PMC5552971.
• Jun SR, Nookaew I, Hauser L, Gorin A. Assessment of genome annotation using gene function similarity within the gene neighborhood. BMC bioinformatics. 2017 18(1):345. PMID: 28724412. PMCID: PMC5517811.
• Zhang Q, Jun SR, Leuze M, [et al.]. Viral Phylogenomics Using an Alignment-Free Method: A Three-Step Approach to Determine Optimal Length of k-mer. Scientific reports. 2017 7:40712. PMID: 28102365. PMCID: PMC5244389.
• Song IS, Han K, Park YM, [et al., including Jun SH]. Severe Periodontitis Is Associated with Insulin Resistance in Non-abdominal Obese Adults. The Journal of clinical endocrinology and metabolism. 2016 101(11):4251-4259. PMID: 27598510.