Viji Mohan Seenivasan, PhD, MBA

Research Program: Cancer Therapeutics Faculty Rank: Assistant Staff Scientist Campus: University of Arkansas for Medical Sciences College: College of Pharmacy Department: Radiation Health

Contact Information

• Email Address: VSridharan@uams.edu

Recent Publications

• Nemec-Bakk AS, Sridharan V, Willey JS, [et al.]. Sex-specific effects on the heart from combined exposure to simulated galactic cosmic radiation and hindlimb unloading. Life sciences in space research. 2025 44:38-46. PMID: 39864910. PMCID: PMC11770252.
• Clement K, Nemec-Bakk AS, Jun SR, [et al., including Sridharan V]. Long-term effects of combined exposures to simulated microgravity and galactic cosmic radiation on the mouse lung: sex-specific epigenetic reprogramming. Radiation and environmental biophysics. 2025. PMID: 39841235.
• Bansal S, Li Y, Bansal S, [et al., including Sridharan V]. Genetic Upregulation of Activated Protein C Mitigates Delayed Effects of Acute Radiation Exposure in the Mouse Plasma. Metabolites. 2024 14(5). PMID: 38786722. PMCID: PMC11122730.
• Landes RD, Li C, Sridharan V, [et al.]. A pooled analysis of nine studies in one institution to assess effects of whole heart irradiation in rat models. International journal of radiation biology. 2023:1-9. PMID: 37603396. PMCID: PMC10843572.
• Nemec-Bakk AS, Sridharan V, Seawright JW, [et al.]. Effects of proton and oxygen ion irradiation on cardiovascular function and structure in a rabbit model. Life sciences in space research. 2023 37:78-87. PMID: 37087182. PMCID: PMC10122719.
• Gawali B, Sridharan V, Krager KJ, [et al.]. TLR4-A Pertinent Player in Radiation-Induced Heart Disease?. Genes. 2023 14(5). PMID: 37239362. PMCID: PMC10218711.
• Li Y, Bansal S, Sridharan V, [et al.]. Urinary Metabolomics for the Prediction of Radiation-Induced Cardiac Dysfunction. Metabolites. 2023 13(4). PMID: 37110184. PMCID: PMC10146652.
• Nemec-Bakk AS, Sridharan V, Desai P, [et al.]. Effects of Simulated 5-Ion Galactic Cosmic Radiation on Function and Structure of the Mouse Heart. Life (Basel, Switzerland). 2023 13(3). PMID: 36983950. PMCID: PMC10057791.
• Sridharan V, Krager KJ, Pawar SA, [et al.]. Effects of Whole and Partial Heart Irradiation on Collagen, Mast Cells, and Toll-like Receptor 4 in the Mouse Heart. Cancers. 2023 15(2). PMID: 36672353. PMCID: PMC9856613.
• Nemec-Bakk AS, Sridharan V, Landes RD, [et al.]. Effects of low-dose oxygen ions on cardiac function and structure in female C57BL/6J mice. Life sciences in space research. 2022 32:105-112. PMID: 35065756. PMCID: PMC8803400.
• Boerma M, Sridharan V, Krager KJ, Pawar SA. Small animal models of localized heart irradiation. Methods in cell biology. 2022 168:221-234. PMID: 35366984. PMCID: PMC9642084.
• Dina Zita M, Phillips MB, Stuart JD, [et al., including Sridharan V]. The M2 Gene Is a Determinant of Reovirus-Induced Myocarditis. Journal of virology. 2021:JVI0187921. PMID: 34757847. PMCID: PMC8791294.
• Nemec-Bakk AS, Sridharan V, Landes RD, [et al.]. Mitigation of late cardiovascular effects of oxygen ion radiation by γ-tocotrienol in a mouse model. Life sciences in space research. 2021 31:43-50. PMID: 34689949. PMCID: PMC8548672.
• Swinton C, Kiffer F, McElroy T, [et al., including Sridharan V]. Effects of (16)O charged-particle irradiation on cognition, hippocampal morphology and mutagenesis in female mice. Behavioural brain research. 2021 407:113257. PMID: 33794227.
• Sridharan V, Johnson KA, Landes RD, [et al.]. Sex-dependent effects of genetic upregulation of activated protein C on delayed effects of acute radiation exposure in the mouse heart, small intestine, and skin. PloS one. 2021 16(5):e0252142. PMID: 34029348. PMCID: PMC8143413.
• Girgis M, Li Y, Jayatilake M, [et al., including Sridharan V]. Short-term metabolic disruptions in urine of mouse models following exposure to low doses of oxygen ion radiation. Journal of environmental science and health. Part C, Toxicology and carcinogenesis. 2021 39(2):234-249. PMID: 33902388. PMCID: PMC9757021.
• Dissmore T, DeMarco AG, Jayatilake M, [et al., including Sridharan V]. Longitudinal metabolic alterations in plasma of rats exposed to low doses of high linear energy transfer radiation. Journal of environmental science and health. Part C, Toxicology and carcinogenesis. 2021 39(2):219-233. PMID: 33902389. PMCID: PMC9896584.
• Van S, Pal S, Garner BR, [et al., including Sridharan V]. Dantrolene Prevents the Lymphostasis Caused by Doxorubicin in the Rat Mesenteric Circulation. Frontiers in pharmacology. 2021 12:727526. PMID: 34483938. PMCID: PMC8415554.
• Mao XW, Nishiyama NC, Byrum SD, [et al., including Sridharan V]. Spaceflight induces oxidative damage to blood-brain barrier integrity in a mouse model. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2020. PMID: 32981077. PMCID: PMC8191453.
• Sridharan V, Seawright JW, Landes RD, [et al.]. Effects of single-dose protons or oxygen ions on function and structure of the cardiovascular system in male Long Evans rats. Life sciences in space research. 2020 26:62-68. PMID: 32718688. PMCID: PMC7387753.
• Upadhyay M, Rajagopal M, Gill K, [et al., including Sridharan V]. Identification of Plasma Lipidome Changes Associated with Low Dose Space-Type Radiation Exposure in a Murine Model. Metabolites. 2020 10(6). PMID: 32560360. PMCID: PMC7345467.
• Unger K, Li Y, Yeh C, [et al., including Sridharan V]. Plasma metabolite biomarkers predictive of radiation induced cardiotoxicity. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 2020. PMID: 32360032. PMCID: PMC7572465.