Reid D Landes, PhD

Research Program: Cancer Biology Faculty Rank: Professor Campus: University of Arkansas for Medical Sciences College: College of Medicine Department: Biostatistics Faculty/Staff

Cancer Research Interest

• Research Interest Statement: I use statistical science to help cancer researchers translate their objectives into statistical terms, then design studies that speak directly to those statistical objectives while using use smaller sample sizes and getting more statistical power. I help them appropriately analyze and report the results from those studies. I have deep expertise in animal studies and substantial expertise in human studies. I also have expertise in N-of-1 trials, and interest in in vitro studies and analyses of –omics data.

Contact Information

• Email Address: RDLANDES@UAMS.EDU
• Profiles Research Networking Software: View Profile

Active Grants

• NIH/Nat. Inst. of General Medical Sciences – 1P20GM152281
  “Center for Molecular Interactions in Cancer (CMIC)”
  Co-Investigator
  3/5/2024 – 12/31/2028
• NIH/Nat. Cancer Institute – 1R37CA282349
  “Ryanodine Receptors as Therapeutic Targets to Prevent Doxorubicin-Induced Lymphatic Dysfunction”
  Co-Investigator
  8/10/2023 – 7/31/2028

Recent Publications

• Pal S, Bagchi AK, Henry DS, [et al., including Landes RD]. Rhythmic Contractions of Lymph Vessels and Lymph Flow Are Disrupted in Hypertensive Rats. Hypertension (Dallas, Tex. : 1979). 2024. PMID: 39502071.
• Landes RD. How cage effects can hurt statistical analyses of completely randomized designs. Laboratory animals. 2024 58(5):476-480. PMID: 39315617.
• Burns J, Landes RD, Pillai L, Virmani T. Tandem gait step-width increases more rapidly in more severely affected people with Parkinson's disease. Parkinsonism & related disorders. 2024 127:107078. PMID: 39096549. PMCID: PMC11449637.
• Rose S, Landes RD, Vyas KK, [et al.]. Regulatory T cells and bioenergetics of peripheral blood mononuclear cells linked to pediatric obesity. Immunometabolism (Cobham, Surrey). 2024 6(2):e00040. PMID: 38680993. PMCID: PMC11045398.
• Franks AM, Teeter BS, Davis P, [et al., including Landes RD]. First-year evaluation of a campus-wide, cross-disciplinary scholarly writing development program supported by a center for biomedical research excellence (COBRE). PloS one. 2024 19(10):e0312322. PMID: 39471171. PMCID: PMC11521313.
• Sadler DG, Landes RD, Treas L, [et al.]. Protonophore treatment augments energy expenditure in mice housed at thermoneutrality. Frontiers in physiology. 2024 15:1452986. PMID: 39381330. PMCID: PMC11458463.
• Tas E, Landes RD, Diaz EC, [et al.]. Effects of short-term supervised exercise training on liver fat in adolescents with obesity: a randomized controlled trial. Obesity (Silver Spring, Md.). 2023 31(11):2740-2749. PMID: 37731271. PMCID: PMC11519784.
• Ararat E, Landes RD, Forno E, [et al.]. Metformin use is associated with decreased asthma exacerbations in adolescents and young adults. Pediatric pulmonology. 2023. PMID: 37772681. PMCID: PMC10872793.
• Landes RD, Li C, Sridharan V, [et al.]. A pooled analysis of nine studies in one institution to assess effects of whole heart irradiation in rat models. International journal of radiation biology. 2023:1-9. PMID: 37603396. PMCID: PMC10843572.
• Tsai PF, Oliveto AH, Landes RD, Mancino MJ. Characteristics of patients undergoing medication-assisted -treatment for opioid use disorder and their interest in Tai Chi practice. Journal of opioid management. 2023 19(4):329-341. PMID: 37644791. PMCID: PMC10913153.
• Landes RD, Jurgensen KJ, Skinner WKJ, [et al.]. Feasibility of Reducing Animal Numbers in Radiation Countermeasure Experiments from Historic Levels when using Sample Size Calculations. Radiation research. 2023. PMID: 37327124. PMCID: PMC10513753.
• Nemec-Bakk AS, Sridharan V, Seawright JW, [et al., including Landes RD]. Effects of proton and oxygen ion irradiation on cardiovascular function and structure in a rabbit model. Life sciences in space research. 2023 37:78-87. PMID: 37087182. PMCID: PMC10122719.
• Nemec-Bakk AS, Sridharan V, Desai P, [et al., including Landes RD]. Effects of Simulated 5-Ion Galactic Cosmic Radiation on Function and Structure of the Mouse Heart. Life (Basel, Switzerland). 2023 13(3). PMID: 36983950. PMCID: PMC10057791.
• Virmani T, Pillai L, Glover A, Landes RD. Levodopa responsive gait dynamics in OFF- and ONOFF-state freezing of gait in Parkinson's disease. Clinical parkinsonism & related disorders. 2023 9:100202. PMID: 37288072. PMCID: PMC10241963.
• Ewing LE, Pathak R, Landes RD, [et al.]. Cytogenetic and epigenetic aberrations in peripheral lymphocytes of northwest Arkansas Marshallese. International journal of radiation biology. 2022:1-12. PMID: 35939319. PMCID: PMC9929030.
• Barbosa P, Landes RD, Graw S, [et al.]. Effect of excess weight and insulin resistance on DNA methylation in prepubertal children. Scientific reports. 2022 12(1):8430. PMID: 35589784. PMCID: PMC9120504.
• Nemec-Bakk AS, Sridharan V, Landes RD, [et al.]. Effects of low-dose oxygen ions on cardiac function and structure in female C57BL/6J mice. Life sciences in space research. 2022 32:105-112. PMID: 35065756. PMCID: PMC8803400.
• Landes RD, Glover A, Pillai L, [et al.]. Levodopa ONOFF-state freezing of gait: Defining the gait and non-motor phenotype. PloS one. 2022 17(6):e0269227. PMID: 35653359. PMCID: PMC9162361.
• Nemec-Bakk AS, Sridharan V, Landes RD, [et al.]. Mitigation of late cardiovascular effects of oxygen ion radiation by γ-tocotrienol in a mouse model. Life sciences in space research. 2021 31:43-50. PMID: 34689949. PMCID: PMC8548672.
• Yarlagadda L, Boerma M, Gundarlapalli S, [et al., including Landes RD]. Salvage Autologous Stem Cell Transplantation in Daratumumab-Refractory Multiple Myeloma. Cancers. 2021 13(16). PMID: 34439174. PMCID: PMC8392190.
• Haruta D, Landes RD, Hida A, [et al.]. Relationship Between Radiation Exposure and Incident Atrial Fibrillation Among Atomic Bomb Survivors. Circulation reports. 2021 3(7):381-387. PMID: 34250279. PMCID: PMC8258179.
• Wang J, Garg S, Landes RD, [et al.]. Differential Recovery of Small Intestinal Segments after Partial-Body Irradiation in Non-Human Primates. Radiation research. 2021. PMID: 34043805. PMCID: PMC8440418.
• Sadhukhan R, Majumdar D, Garg S, [et al., including Landes RD]. Simultaneous exposure to chronic irradiation and simulated microgravity differentially alters immune cell phenotype in mouse thymus and spleen. Life sciences in space research. 2021 28:66-73. PMID: 33612181. PMCID: PMC7900614.
• Sridharan V, Johnson KA, Landes RD, [et al.]. Sex-dependent effects of genetic upregulation of activated protein C on delayed effects of acute radiation exposure in the mouse heart, small intestine, and skin. PloS one. 2021 16(5):e0252142. PMID: 34029348. PMCID: PMC8143413.
• Jurgensen KJ, Skinner WKJ, Oronsky B, [et al., including Landes RD]. RRx-001 Radioprotection: Enhancement of Survival and Hematopoietic Recovery in Gamma-Irradiated Mice. Frontiers in pharmacology. 2021 12:676396. PMID: 33967816. PMCID: PMC8100686.
• Hays L, McSweeney J, Mitchell A, [et al., including Landes RD]. Recruitment Issues in Emerging Adult Populations: Focus on Adult Congenital Heart Disease. Nursing reports (Pavia, Italy). 2020 10(2):135-145. PMID: 34968358. PMCID: PMC8608111.
• Hays LH, McSweeney JC, Mitchell A, [et al., including Landes RD]. Self-management Needs of Adults With Congenital Heart Disease. The Journal of cardiovascular nursing. 2020 35(6):E33-E43. PMID: 32453276.
• Landes RD. Comment on "Designing Robust N-of-1 Studies for Precision Medicine: Simulation Study and Design Recommendations". Journal of medical Internet research. 2020 22(9):e16179. PMID: 32930671. PMCID: PMC7525463.
• Sridharan V, Seawright JW, Landes RD, [et al.]. Effects of single-dose protons or oxygen ions on function and structure of the cardiovascular system in male Long Evans rats. Life sciences in space research. 2020 26:62-68. PMID: 32718688. PMCID: PMC7387753.
• Chen HF, Landes RD, Schuldt RF. Quality Performance of Rural and Urban Home Health Agencies: Implications for Rural Add-On Payment Policies. The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association. 2020 36(3):423-432. PMID: 32022948.
• Tang J, Landes RD. Some t-tests for N-of-1 trials with serial correlation. PloS one. 2020 15(2):e0228077. PMID: 32017772. PMCID: PMC6999905.