Analiz Rodriguez, MD, PhD

Full Member

Research Program:

Cancer Therapeutics

Faculty Rank:

Associate Professor

Campus:

University of Arkansas for Medical Sciences

College:

College of Medicine

Department:

Neurosurgery Faculty

Contact Information

Email Address: ARODRIGUEZ@UAMS.EDU
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Open Clinical Trials

“A Multicenter Observational Study of GammaTile Surgically Targeted RadiationTherapy (STaRT) in Intracranial Brain Neoplasms” (NCT04427384)

Active Grants

NIH/Nat. Cancer Institute – 1R03CA289645
“Development of immunocompetent melanoma brain metastases organoids”
Principal Investigator
3/6/2024 – 2/28/2026

Recent Publications

Ledford A, Rodriguez A, Lipinski L, [et al.]. Functional prediction of response to therapy prior to therapeutic intervention is associated with improved survival in patients with high-grade glioma. Scientific reports. 2024 14(1):19474. PMID: 39198514. PMCID: PMC11358395.
Morris M, Ararat K, Cutshall H, [et al., including Rodriguez A]. SMARCA4-deficient central nervous system metastases: A case series and systematic review. Journal of neuropathology and experimental neurology. 2024 83(8):638-654. PMID: 38687619.
Mahashabde RV, Bhatti SA, Martin BC, [et al., including Rodriguez A]. Immune checkpoint inhibitors as subsequent treatment in older adults with non-small cell lung cancer and synchronous brain metastases. Translational lung cancer research. 2024 13(7):1620-1634. PMID: 39118898. PMCID: PMC11304147.
Shelton WJ, Santos Horta E, Stephen Nix J, [et al., including Rodriguez A]. Functional precision medicine assay for recurrent meningioma: a proof of principle. Illustrative case. Journal of neurosurgery. Case lessons. 2024 8(5). PMID: 39074389. PMCID: PMC11301594.
Shelton WJ, Mathews AP, Aljiboori K, [et al., including Rodriguez A]. A rare case of atypical intradural extramedullary glioblastoma diagnosed utilizing next-generation sequencing and methylation profiling: illustrative case. Journal of neurosurgery. Case lessons. 2024 7(16). PMID: 38621302. PMCID: PMC11023011.
Chiang VL, Pugazenthi S, Leidig WA, [et al., including Rodriguez A]. Laser interstitial thermal therapy for new and recurrent meningioma: a prospective and retrospective case series. Journal of neurosurgery. 2024:1-11. PMID: 38457795.
Mathews AP, Shelton WJ, Horta ES, [et al., including Rodriguez A]. Operative planning for a functional precision medicine assay of recurrent high-grade glioma: illustrative case. Journal of neurosurgery. Case lessons. 2024 7(7). PMID: 38346299. PMCID: PMC10865468.
Shelton WJ, Zandpazandi S, Nix JS, [et al., including Rodriguez A]. Long-read sequencing for brain tumors. Frontiers in oncology. 2024 14:1395985. PMID: 38915364. PMCID: PMC11194609.
Rodriguez A, Ahluwalia MS, Bettegowda C, [et al.]. Toward standardized brain tumor tissue processing protocols in neuro-oncology: a perspective for gliomas and beyond. Frontiers in oncology. 2024 14:1471257. PMID: 39376983. PMCID: PMC11456923.
Urbaniak A, Bathula C, Chauhan J, [et al., including Rodriguez A]. Synthesis and Anti-Melanoma Activity of Acryloyl Pyridinone Analogues. Chemistry & biodiversity. 2023:e202301550. PMID: 37994208. PMCID: PMC10984326.
McCrury M, Swafford K, Shuttleworth SL, [et al., including Rodriguez A]. Bifunctional inhibitor reveals NEK2 as a therapeutic target and regulator of oncogenic pathways in lymphoma. Molecular cancer therapeutics. 2023. PMID: 37816504. PMCID: PMC10932871.
Langston RG, Pinckard-Dover H, Guzman G, [et al., including Rodriguez A]. Intracranial hematolymphoid malignancies: A case series with molecular characterization. Clinical neurology and neurosurgery. 2023 233:107928. PMID: 37573681.
Mahashabde R, Bhatti SA, Martin BC, [et al., including Rodriguez A]. Real-World Survival of First-Line Immune Checkpoint Inhibitor Treatment Versus Chemotherapy in Older Patients With Non-Small-Cell Lung Cancer and Synchronous Brain Metastases. JCO oncology practice. 2023:OP2300042. PMID: 37729600.
Pastorino NG, Tomatsu S, Lin A, [et al., including Rodriguez A]. Using the Chick Embryo Brain as a Model for In Vivo and Ex Vivo Analyses of Human Glioblastoma Cell Behavior. Journal of visualized experiments : JoVE. 2023(195). PMID: 37306427.
Nassiri F, Patil V, Yefet LS, [et al., including Rodriguez A]. Oncolytic DNX-2401 virotherapy plus pembrolizumab in recurrent glioblastoma: a phase 1/2 trial. Nature medicine. 2023. PMID: 37188783. PMCID: PMC10287560.
Guzman G, Pellot K, Reed MR, Rodriguez A. CAR T-cells to treat brain tumors. Brain research bulletin. 2023 196:76-98. PMID: 36841424.
Adler FR, Anderson ARA, Bhushan A, [et al., including Rodriguez A]. Modeling collective cell behavior in cancer: Perspectives from an interdisciplinary conversation. Cell systems. 2023 14(4):252-257. PMID: 37080161. PMCID: PMC10760508.
Charles AJ, Seas A, Corley J, [et al., including Rodriguez A]. Promoting diversity in neurosurgery through a virtual symposium. Journal of neurosurgery. 2023:1-8. PMID: 36905659.
Guzman G, Reed MR, Bielamowicz K, [et al., including Rodriguez A]. CAR-T Therapies in Solid Tumors: Opportunities and Challenges. Current oncology reports. 2023. PMID: 36853475. PMCID: PMC10110629.
Al-Hamaly MA, Turner LT, Rivera-Martinez A, [et al., including Rodriguez A]. Zebrafish Cancer Avatars: A Translational Platform for Analyzing Tumor Heterogeneity and Predicting Patient Outcomes. International journal of molecular sciences. 2023 24(3). PMID: 36768609. PMCID: PMC9916713.
Velleuer E, Domínguez-Hüttinger E, Rodríguez A, [et al.]. Concepts of multi-level dynamical modelling: understanding mechanisms of squamous cell carcinoma development in Fanconi anemia. Frontiers in genetics. 2023 14:1254966. PMID: 38028610. PMCID: PMC10652399.
Porter A, Brown CC, Rodriguez A, [et al.]. Variation in Time Between Testing Positive for COVID-19 and Hospital Admission by Race/Ethnicity and Insurance Status. Journal of health care for the poor and underserved. 2023 34(4):1290-1304. PMID: 38661756. PMCID: PMC11101062.
Sanders LM, Chandra R, Zebarjadi N, [et al., including Rodriguez A]. Machine learning multi-omics analysis reveals cancer driver dysregulation in pan-cancer cell lines compared to primary tumors. Communications biology. 2022 5(1):1367. PMID: 36513728. PMCID: PMC9747808.
Urbaniak A, Reed MR, Heflin B, [et al., including Rodriguez A]. Anti-glioblastoma activity of monensin and its analogs in an organoid model of cancer. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2022 153:113440. PMID: 36076555. PMCID: PMC9472755.
Rennert RC, Stephens ML, Palmer AW, [et al., including Rodriguez A]. Basilar decompression via a far lateral transcondylar approach: technical note. Acta neurochirurgica. 2022. PMID: 35867183.
Tripathi SD, Parker PD, Prabhu AV, [et al., including Rodriguez A]. An Examination of Patients and Caregivers on Reddit Navigating Brain Cancer: Content Analysis of the Brain Tumor Subreddit. JMIR cancer. 2022 8(2):e35324. PMID: 35731559. PMCID: PMC9260533.
Asfaw ZK, Rodriguez A, Hodges TR, [et al.]. Diversity within the neurosurgical oncology workforce in the United States: A cross-sectional study with proposed strategies to pave the path forward. Neuro-oncology. 2022. PMID: 35705107. PMCID: PMC9825340.
Helton M, Thomas K, Sexton K, [et al., including Rodriguez A]. Treatment Trends and Inpatient Mortality in Isolated Severe Traumatic Brain Injury Using the National Trauma Data Bank. World neurosurgery. 2022. PMID: 35597537.
Brown CE, Rodriguez A, Palmer J, [et al.]. Off-the-shelf, steroid-resistant, IL13Rα2-specific CAR T cells for treatment of glioblastoma. Neuro-oncology. 2022. PMID: 35100373. PMCID: PMC9340633.
Reed MR, Lyle AG, De Loose A, [et al., including Rodriguez A]. A Functional Precision Medicine Pipeline Combines Comparative Transcriptomics and Tumor Organoid Modeling to Identify Bespoke Treatment Strategies for Glioblastoma. Cells. 2021 10(12). PMID: 34943910. PMCID: PMC8699481.
Rodriguez A. Misogynoir. Journal of graduate medical education. 2021 13(6):795-796. PMID: 35070091. PMCID: PMC8672849.
Wardell CP, Darrigues E, De Loose A, [et al., including Rodriguez A]. Genomic and Transcriptomic Profiling of Brain Metastases. Cancers. 2021 13(22). PMID: 34830758. PMCID: PMC8615723.
Darrigues E, Zhao EH, De Loose A, [et al., including Rodriguez A]. Biobanked Glioblastoma Patient-Derived Organoids as a Precision Medicine Model to Study Inhibition of Invasion. International journal of molecular sciences. 2021 22(19). PMID: 34639060. PMCID: PMC8509225.
Hundley KN, Pait TG, Rodriguez A, Day JD. Dr. Louise Eisenhardt's personal notes: how she and Dr. Cushing collected data and followed patients. Journal of neurosurgery. 2021:1-6. PMID: 34560651.
Sanders S, Herpai DM, Rodriguez A, [et al.]. The Presence and Potential Role of ALDH1A2 in the Glioblastoma Microenvironment. Cells. 2021 10(9). PMID: 34572134. PMCID: PMC8468822.
Nduom EK, Gephart MH, Chheda MG, [et al., including Rodriguez A]. Re-evaluating Biopsy for Recurrent Glioblastoma: A Position Statement by the Christopher Davidson Forum Investigators. Neurosurgery. 2021 89(1):129-132. PMID: 33862619.
Rennert RC, Brandel MG, Stephens ML, [et al., including Rodriguez A]. Surgical Relevance of the Suprameatal Tubercle During Superior Petrosal Vein-Sparing Trigeminal Nerve Microvascular Decompression. Operative neurosurgery (Hagerstown, Md.). 2021 20(6):E410-E416. PMID: 33647963.
Nieblas-Bedolla E, Christophers B, Williams JR, [et al., including Rodriguez A]. Racial and ethnic disparities among children with primary central nervous system tumors in the US. Journal of neuro-oncology. 2021 152(3):451-466. PMID: 33774801.
Darrigues E, Elberson BW, De Loose A, [et al., including Rodriguez A]. Brain Tumor Biobank Development for Precision Medicine: Role of the Neurosurgeon. Frontiers in oncology. 2021 11:662260. PMID: 33981610. PMCID: PMC8108694.
Prabhu AV, Lee M, Galhardo E, [et al., including Rodriguez A]. Pulsed reduced dose-rate radiotherapy for previously irradiated tumors in the brain and spine. Surgical neurology international. 2021 12:280. PMID: 34221611. PMCID: PMC8247706.
Langston RG, Wardell CP, Palmer A, [et al., including Rodriguez A]. Primary glioblastoma of the cauda equina with molecular and histopathological characterization: Case report. Neuro-oncology advances. 2021 3(1):vdab154. PMID: 34765976. PMCID: PMC8577522.
Rennert RC, Khani M, Thomas K, [et al., including Rodriguez A]. Transsulcal parafascicular brain path-assisted approach to subcortical lesions: 2-dimensional operative video. Surgical neurology international. 2021 12:107. PMID: 33880212. PMCID: PMC8053449.
Gunasekaran A, Somasundarum A, Abu-Rmaileh M, [et al., including Rodriguez A]. The Original Cushing Society: A Historical Review of the Senior Society's First 6 Meetings. World neurosurgery. 2020. PMID: 33307257.
Langston RG, Zhao EH, Wong KH, Rodriguez A. Recent trends in NIH funding for top surgeon-scientists. American journal of surgery. 2020. PMID: 33309253.
Taylor EM, Byrum SD, Edmondson JL, [et al., including Rodriguez A]. Proteogenomic analysis of melanoma brain metastases from distinct anatomical sites identifies pathways of metastatic progression. Acta neuropathologica communications. 2020 8(1):157. PMID: 32891176. PMCID: PMC7487560.
Khani M, Hundley K, Morris TW 3rd, [et al., including Rodriguez A]. Surgical Treatment of Symptomatic Small Medial Petrous Meningiomas Causing Trigeminal Neuralgia. World neurosurgery. 2020 139:e761-e768. PMID: 32360921.
Porter A, Brown CC, Thomas K, [et al., including Rodriguez A]. Association of Insurance Status With Treatment and Outcomes in Pediatric Patients With Severe Traumatic Brain Injury. Critical care medicine. 2020 48(7):e584-e591. PMID: 32427612.
Wongsurawat T, Jenjaroenpun P, De Loose A, [et al., including Rodriguez A]. A novel Cas9-targeted long-read assay for simultaneous detection of IDH1/2 mutations and clinically relevant MGMT methylation in fresh biopsies of diffuse glioma. Acta neuropathologica communications. 2020 8(1):87. PMID: 32563269. PMCID: PMC7305623.