Samantha L Kendrick, PhD, MS

Research Program: Cancer Biology Faculty Rank: Assistant Professor Campus: University of Arkansas for Medical Sciences College: College of Medicine Department: Biochemistry & Molecular Biology

Cancer Research Interest

• Disease Site Focus: Leukemia/ Lymphoma
• Research Focus Area: Treatment, Carcinogenesis
• Type of Research: Basic

Contact Information

• Email Address: SKENDRICK@UAMS.EDU
• Profiles Research Networking Software: View Profile

Active Grants

• US Department of Defense – W81XWH2211031
  “Targeting unique DNA structures to repress ”
  Principal Investigator
  09/15/22 – 09/14/25
• NIH/Nat. Inst. of General Medical Sciences – P20GM121293
  “Targeting oncogenic regulation through unique DNA ”
  Principal Investigator
  07/01/22 – 06/30/23

Publications

• Chen J, Wang Z, Phuc T, [et al., including Kendrick S]. Oncolytic strategy using new bifunctional HDACs/BRD4 inhibitors against virus-associated lymphomas. PLoS pathogens. 2023 19(1):e1011089. PMID: 36638143. PMCID: PMC9879403.
• Swafford K, Acharya B, Xu YZ, [et al., including Kendrick S]. Targeting a Novel G-Quadruplex in the CARD11 Oncogene Promoter with Naptho(2,1-b)furan-1-ethanol,2-nitro- Requires the Nitro Group. Genes. 2022 13(7). PMID: 35885931. PMCID: PMC9321325.
• Chen J, Barrett L, Lin Z, [et al., including Kendrick S]. Identification of natural compounds tubercidin and lycorine HCl against small-cell lung cancer and BCAT1 as a therapeutic target. Journal of cellular and molecular medicine. 2022. PMID: 35318805. PMCID: PMC9077304.
• Chen J, Dai L, Kendrick S, [et al.]. The anti-COVID-19 Drug Remdesivir Promotes Oncogenic Herpesviruses Reactivation through Regulation of Intracellular Signaling Pathways. Antimicrobial agents and chemotherapy. 2022:aac0239521. PMID: 35041508. PMCID: PMC8923226.
• Mohan M, Kendrick S, Szabo A, [et al.]. Clinical implications of loss of bone marrow minimal residual disease negativity in multiple myeloma. Blood advances. 2021. PMID: 34807986. PMCID: PMC8945288.
• Mohan M, Szabo A, Yarlagadda N, [et al., including Kendrick S]. Persistent bone marrow minimal residual disease as a "high-risk" disease feature in multiple myeloma. American journal of hematology. 2021. PMID: 34050985.
• Mohan M, Tackett A, Kumar M, [et al., including Kendrick S]. Bone remineralization of lytic lesions in multiple myeloma - The Arkansas experience. Bone. 2021 146:115876. PMID: 33556629. PMCID: PMC8627246.
• Brown SL, Kendrick S. The i-Motif as a Molecular Target: More Than a Complementary DNA Secondary Structure. Pharmaceuticals (Basel, Switzerland). 2021 14(2). PMID: 33513764. PMCID: PMC7911047.
• Xu YZ, Jenjaroenpun P, Wongsurawat T, [et al., including Kendrick S]. Activation-induced cytidine deaminase localizes to G-quadruplex motifs at mutation hotspots in lymphoma. NAR cancer. 2020 2(4):zcaa029. PMID: 33094287. PMCID: PMC7556405.
• Shponka V, Reveles CY, Alam S, [et al., including Kendrick S]. Frequent expression of activation-induced cytidine deaminase in diffuse large B-cell lymphoma tissues from persons living with HIV. AIDS (London, England). 2020 34(14):2025-2035. PMID: 32773475. PMCID: PMC9306295.
• Storey AJ, Naceanceno KS, Lan RS, [et al., including Kendrick S]. ProteoViz: a tool for the analysis and interactive visualization of phosphoproteomics data. Molecular omics. 2020. PMID: 32347222. PMCID: PMC7423749.
• Chen J, Forrest J, post s, [et al., including Kendrick S]. Mechanistic Insights into Chemoresistance Mediated by Oncogenic Viruses in Lymphomas. Viruses. 2019 11(12). PMID: 31888174. PMCID: PMC6950054.
• Maguire A, Chen X, Wisner L, [et al., including Kendrick S]. Enhanced DNA repair and genomic stability identify a novel HIV-related diffuse large B-cell lymphoma signature. International journal of cancer. 2019 145(11):3078-3088. PMID: 31044434.
• Kendrick S, Muranyi A, Gokhale V, [et al.]. Simultaneous Drug Targeting of the Promoter MYC G-Quadruplex and BCL2 i-Motif in Diffuse Large B-Cell Lymphoma Delays Tumor Growth. Journal of medicinal chemistry. 2017 60(15):6587-6597. PMID: 28605593.
• Kendrick S, Rimsza LM, Scott DW, [et al.]. Aberrant cytoplasmic expression of MHCII confers worse progression free survival in diffuse large B-cell lymphoma. Virchows Archiv : an international journal of pathology. 2017 470(1):113-117. PMID: 27888357.
• Kendrick S, Kang HJ, Alam MP, [et al.]. Correction to "The Dynamic Character of the BCL2 Promoter i-Motif Provides a Mechanism for Modulation of Gene Expression by Compounds That Bind Selectively to the Alternative DNA Hairpin Structure". Journal of the American Chemical Society. 2016 138(35):11408. PMID: 27571358. PMCID: PMC8154439.