Vladimir P Zharov, PhD, DSc

Research Program: Cancer Therapeutics Faculty Rank: Professor Campus: University of Arkansas for Medical Sciences College: College of Medicine Department: Otolaryngology

Cancer Research Interest

• Disease Site Focus: Breast, Cutaneous/Melanoma
• Research Focus Area: Diagnosis/ Prognosis
• Type of Research: Clinical

Contact Information

• Email Address: ZHAROVVLADIMIRP@UAMS.EDU
• Profiles Research Networking Software: View Profile

Publications

• Jawad HJ, Yadem AC, Menyaev YA, [et al., including Zharov VP]. Towards rainbow portable Cytophone with laser diodes for global disease diagnostics. Scientific reports. 2022 12(1):8671. PMID: 35606373. PMCID: PMC9126638.
• Nedosekin DA, Chen T, Ayyadevara S, [et al., including Zharov VP]. Label-free photothermal disruption of cytotoxic aggregates rescues pathology in a C. elegans model of Huntington's disease. Scientific reports. 2021 11(1):19732. PMID: 34611196. PMCID: PMC8492664.
• Mokrousov MD, Thompson W, Ermilov SA, [et al., including Zharov VP]. Indocyanine green dye based bimodal contrast agent tested by photoacoustic/fluorescence tomography setup. Biomedical optics express. 2021 12(6):3181-3195. PMID: 34221653. PMCID: PMC8221961.
• Kozlova A, Bratashov D, Grishin O, [et al., including Zharov VP]. Dynamic blood flow phantom for in vivo liquid biopsy standardization. Scientific reports. 2021 11(1):1185. PMID: 33441866. PMCID: PMC7806591.
• Nozdriukhin D, Besedina N, Chernyshev V, [et al., including Zharov V]. Gold nanoparticle-carbon nanotube multilayers on silica microspheres: Optoacoustic-Raman enhancement and potential biomedical applications. Materials science & engineering. C, Materials for biological applications. 2021 120:111736. PMID: 33545879.
• Vogl TJ, Riegelbauer LJ, Oppermann E, [et al., including Zharov VP]. Early dynamic changes in circulating tumor cells and prognostic relevance following interventional radiological treatments in patients with hepatocellular carcinoma. PloS one. 2021 16(2):e0246527. PMID: 33577574. PMCID: PMC7880472.
• Novoselova MV, Abakumova TO, Khlebtsov BN, [et al., including Zharov VP]. Optical clearing for photoacoustic lympho- and angiography beyond conventional depth limit in vivo. Photoacoustics. 2020 20:100186. PMID: 32637316. PMCID: PMC7327268.
• Han M, Watts JA, Jamshidi-Parsian A, [et al., including Zharov VP]. In Vivo Lymphatic Circulating Tumor Cells and Progression of Metastatic Disease. Cancers. 2020 12(10). PMID: 33028044. PMCID: PMC7650582.
• Genina EA, Surkov YI, Serebryakova IA, [et al., including Zharov VP]. Rapid Ultrasound Optical Clearing of Human Light and Dark Skin. IEEE transactions on medical imaging. 2020 39(10):3198-3206. PMID: 32310764.
• Han M, Watts JA, Jamshidi-Parsian A, [et al., including Zharov VP]. Lymph Liquid Biopsy for Detection of Cancer Stem Cells. Cytometry. Part A : the journal of the International Society for Analytical Cytology. 2020. PMID: 32869909. PMCID: PMC9237844.
• Harrington WN, Nolan J, Nedosekin DA, [et al., including Zharov VP]. Real-Time Monitoring of Bacteria Clearance From Blood in a Murine Model. Cytometry. Part A : the journal of the International Society for Analytical Cytology. 2020 97(7):706-712. PMID: 31769208.
• Darrigues E, Nima ZA, Nedosekin DA, [et al., including Zharov VP]. Tracking Gold Nanorods' Interaction with Large 3D Pancreatic-Stromal Tumor Spheroids by Multimodal Imaging: Fluorescence, Photoacoustic, and Photothermal Microscopies. Scientific reports. 2020 10(1):3362. PMID: 32099027. PMCID: PMC7042370.
• Steenbergen W, Zharov VP. Towards Reaching the Total Blood Volume by in vivo Flow Cytometry and Theranostics. Cytometry. Part A : the journal of the International Society for Analytical Cytology. 2019 95(12):1223-1225. PMID: 31670875. PMCID: PMC6972999.
• Stolarz AJ, Sarimollaoglu M, Marecki JC, [et al., including Zharov VP]. Doxorubicin Activates Ryanodine Receptors in Rat Lymphatic Muscle Cells to Attenuate Rhythmic Contractions and Lymph Flow. The Journal of pharmacology and experimental therapeutics. 2019 371(2):278-289. PMID: 31439806. PMCID: PMC6815939.
• Sindeeva OA, Verkhovskii RA, Sarimollaoglu M, [et al., including Zharov VP]. New Frontiers in Diagnosis and Therapy of Circulating Tumor Markers in Cerebrospinal Fluid In Vitro and In Vivo. Cells. 2019 8(10). PMID: 31581745. PMCID: PMC6830088.
• Mokrousov MD, Novoselova MV, Nolan J, [et al., including Zharov VP]. Amplification of photoacoustic effect in bimodal polymer particles by self-quenching of indocyanine green. Biomedical optics express. 2019 10(9):4775-4789. PMID: 31565524. PMCID: PMC6757463.
• Harrington WN, Novoselova MV, Bratashov DN, [et al., including Zharov VP]. Photoswitchable Spasers with a Plasmonic Core and Photoswitchable Fluorescent Proteins. Scientific reports. 2019 9(1):12439. PMID: 31455790. PMCID: PMC6712012.
• Galanzha EI, Menyaev YA, Yadem AC, [et al., including Zharov VP]. In vivo liquid biopsy using Cytophone platform for photoacoustic detection of circulating tumor cells in patients with melanoma. Science translational medicine. 2019 11(496). PMID: 31189720. PMCID: PMC9235419.
• Nolan J, Nedosekin DA, Galanzha EI, Zharov VP. Detection of Apoptotic Circulating Tumor Cells Using in vivo Fluorescence Flow Cytometry. Cytometry. Part A : the journal of the International Society for Analytical Cytology. 2019 95(6):664-671. PMID: 30508273. PMCID: PMC9257981.
• Novoselova MV, Bratashov DN, Sarimollaoglu M, [et al., including Zharov VP]. Photoacoustic and fluorescent effects in multilayer plasmon-dye interfaces. Journal of biophotonics. 2019 12(4):e201800265. PMID: 30511464. PMCID: PMC9241577.
• Nima ZA, Watanabe F, Jamshidi-Parsian A, [et al., including Zharov VP]. Bioinspired magnetic nanoparticles as multimodal photoacoustic, photothermal and photomechanical contrast agents. Scientific reports. 2019 9(1):887. PMID: 30696936. PMCID: PMC6351522.
• Nima ZA, Vang KB, Nedosekin D, [et al., including Zharov V]. Quantification of cellular associated graphene and induced surface receptor responses. Nanoscale. 2019 11(3):932-944. PMID: 30608496. PMCID: PMC9261879.
• Usoltseva LO, Volkov DS, Nedosekin DA, [et al., including Zharov VP]. Absorption spectra of nanodiamond aqueous dispersions by optical absorption and optoacoustic spectroscopies. Photoacoustics. 2018 12:55-66. PMID: 30450280. PMCID: PMC6222039.
• Juratli MA, Menyaev YA, Sarimollaoglu M, [et al., including Zharov VP]. Noninvasive label-free detection of circulating white and red blood clots in deep vessels with a focused photoacoustic probe. Biomedical optics express. 2018 9(11):5667-5677. PMID: 30460154. PMCID: PMC6238938.
• Jawad HJ, Sarimollaoglu M, Biris AS, Zharov VP. Dynamic blood flow phantom with negative and positive photoacoustic contrasts. Biomedical optics express. 2018 9(10):4702-4713. PMID: 30319897. PMCID: PMC6179420.
• Tuchin VV, Zharov VP, Galanzha EI. Biophotonics for lymphatic theranostics in animals and humans. Journal of biophotonics. 2018 11(8):e201811001. PMID: 30006983. PMCID: PMC6548310.
• Sarimollaoglu M, Stolarz AJ, Nedosekin DA, [et al., including Zharov VP]. High-speed microscopy for in vivo monitoring of lymph dynamics. Journal of biophotonics. 2018 11(8):e201700126. PMID: 29232054. PMCID: PMC6314807.
• Sun RW, Tuchin VV, Zharov VP, [et al.]. Current status, pitfalls and future directions in the diagnosis and therapy of lymphatic malformation. Journal of biophotonics. 2018 11(8):e201700124. PMID: 28851128.
• Meeker DG, Wang T, Harrington WN, [et al., including Zharov VP]. Versatility of targeted antibiotic-loaded gold nanoconstructs for the treatment of biofilm-associated bacterial infections. International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group. 2018 34(2):209-219. PMID: 29025325. PMCID: PMC6095133.
• Jenkins SV, Nedosekin DA, Miller EK, [et al., including Zharov VP]. Galectin-1-based tumour-targeting for gold nanostructure-mediated photothermal therapy. International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group. 2018 34(1):19-29. PMID: 28540812. PMCID: PMC5872830.
• Nima ZA, Alwbari AM, Dantuluri V, [et al., including Zharov VP]. Targeting nano drug delivery to cancer cells using tunable, multi-layer, silver-decorated gold nanorods. Journal of applied toxicology : JAT. 2017 37(12):1370-1378. PMID: 28730725.
• Nedosekin DA, Nolan J, Cai C, [et al., including Zharov VP]. In vivo noninvasive analysis of graphene nanomaterial pharmacokinetics using photoacoustic flow cytometry. Journal of applied toxicology : JAT. 2017 37(11):1297-1304. PMID: 28524252. PMCID: PMC5610617.
• Koonce NA, Juratli MA, Cai C, [et al., including Zharov V]. Real-time monitoring of circulating tumor cell (CTC) release after nanodrug or tumor radiotherapy using in vivo flow cytometry. Biochemical and biophysical research communications. 2017 492(3):507-512. PMID: 28822765. PMCID: PMC5743220.
• Vang KB, Safina I, Darrigues E, [et al., including Zharov VP]. Modifying Dendritic Cell Activation with Plasmonic Nano Vectors. Scientific reports. 2017 7(1):5513. PMID: 28710434. PMCID: PMC5511287.
• Galanzha EI, Weingold R, Nedosekin DA, [et al., including Zharov VP]. Spaser as a biological probe. Nature communications. 2017 8:15528. PMID: 28593987. PMCID: PMC5472166.
• Nedosekin DA, Fahmi T, Nima ZA, [et al., including Zharov VP]. Photoacoustic in vitro flow cytometry for nanomaterial research. Photoacoustics. 2017 6:16-25. PMID: 28417068. PMCID: PMC5387917.
• Darrigues E, Nima ZA, Majeed W, [et al., including Zharov VP]. Raman spectroscopy using plasmonic and carbon-based nanoparticles for cancer detection, diagnosis, and treatment guidance.Part 1: Diagnosis. Drug metabolism reviews. 2017 49(2):212-252. PMID: 28264609.
• Jenkins SV, Nima ZA, Vang KB, [et al., including Zharov VP]. Triple-negative breast cancer targeting and killing by EpCAM-directed, plasmonically active nanodrug systems. NPJ precision oncology. 2017 1(1):27. PMID: 29872709. PMCID: PMC5871908.
• Zharov VP, Latyshev AS. Laser Non-Contact Drug Delivery Methods: Mathematical and Experimental Substantiation. Critical reviews in biomedical engineering. 2017 45(1-6):303-317. PMID: 29953382.
• Zharov VP, Menyaev YA, Kabisov RK, [et al.]. Study on the Design and Application of Combining Low-Frequency Ultrasound with Laser Radiation in Surgery and Therapy. Critical reviews in biomedical engineering. 2017 45(1-6):153-170. PMID: 29953377.
• Harrington WN, Haji MR, Galanzha EI, [et al., including Zharov VP]. Photoswitchable non-fluorescent thermochromic dye-nanoparticle hybrid probes. Scientific reports. 2016 6:36417. PMID: 27824110. PMCID: PMC5099817.
• Menyaev YA, Carey KA, Nedosekin DA, [et al., including Zharov VP]. Preclinical photoacoustic models: application for ultrasensitive single cell malaria diagnosis in large vein and artery. Biomedical optics express. 2016 7(9):3643-3658. PMID: 27699126. PMCID: PMC5030038.
• Kotagiri N, Sakon J, Han H, [et al., including Zharov VP]. Fluorescent ampicillin analogues as multifunctional disguising agents against opsonization. Nanoscale. 2016 8(25):12658-67. PMID: 26935543. PMCID: PMC4919181.