Shmuel Yaccoby, PhD

Research Program: Cancer Biology Faculty Rank: Professor Campus: University of Arkansas for Medical Sciences College: College of Medicine Department: Internal Med Myeloma Research

Cancer Research Interest

• Disease Site Focus: Multiple Myeloma
• Research Focus Area: Health Disparities, Prevention, Treatment, Informatics, Detection, Diagnosis/ Prognosis
• Type of Research: Basic
• Research Interest Statement: Pathogenesis of multiple myeloma, tumor microenvironment, bone marrow mesenchymal stem cells, and tumor initiating cells.

Contact Information

• Email Address: YACCOBYSHMUEL@UAMS.EDU
• Profiles Research Networking Software: View Profile

Active Grants

• US Department of Defense – W81XWH2110601
  “Role of novel myeloma subpopulations in the disease progression and drug resistance”
  Principal Investigator
  9/30/2021 – 9/29/2025

Recent Publications

• Ling W, Johnson SK, Mehdi SJ, [et al., including Yaccoby S]. EDNRA-Expressing Mesenchymal Cells Are Expanded in Myeloma Interstitial Bone Marrow and Associated with Disease Progression. Cancers. 2023 15(18). PMID: 37760488. PMCID: PMC10526862.
• Mehdi SJ, Ghatak K, Ling W, [et al., including Yaccoby S]. Growth and dormancy control of myeloma cells by mesenchymal stem cells. Leukemia research. 2023 133:107355. PMID: 37499483.
• Mikulasova A, Kent D, Trevisan-Herraz M, [et al., including Yaccoby S]. Epigenomic translocation of H3K4me3 broad domains over oncogenes following hijacking of super-enhancers. Genome research. 2021. PMID: 34933939. PMCID: PMC9341503.
• Schinke CD, Boerma M, Bird JT, [et al., including Yaccoby S]. PHF19 inhibition as a therapeutic target in multiple myeloma. Current research in translational medicine. 2021 69(3):103290. PMID: 33894670. PMCID: PMC8316274.