Jerry Ware, PhD

Research Program: Cancer Biology Faculty Rank: Professor Campus: University of Arkansas for Medical Sciences College: College of Medicine Department: Physiology & Cell Biology

Cancer Research Interest

• Research Interest Statement: I am a vascular biologist with interests in the dynamic interface of coagulation, inflammation, and cancer. I'm also the basic science module director for Hematology/Oncology delivered to medical students in the Spring of their first year. Specific to cancer, our lab focuses on circulating platelets and their ability to support tumor cell/platelet interactions that impact metastasis.

Contact Information

• Email Address: JWARE@UAMS.EDU
• Profiles Research Networking Software: View Profile

Active Grants

• NIH/Nat. Inst. of Allergy & Infectious Diseases – 1U01AI170039
  “Platelets in radiation-induced immune dysregulation”
  Principal Investigator
  07/25/22 – 05/31/27

Publications

• Davis OM, Kore R, Moore A, [et al., including Ware J]. Platelet Count and Platelet Volume in Patients with Chronic Kidney Disease. Journal of the American Society of Nephrology : JASN. 2023. PMID: 37677933. PMCID: PMC10631596.
• Jain N, Corken A, Arthur JM, [et al., including Ware J]. Ticagrelor inhibits platelet aggregation and reduces inflammatory burden more than clopidogrel in patients with stages 4 or 5 chronic kidney disease. Vascular pharmacology. 2023 148:107143. PMID: 36682595. PMCID: PMC9998358.
• Corken A, Ware J, Dai J, [et al.]. Platelet-Dependent Inflammatory Dysregulation in Patients with Stages 4 or 5 Chronic Kidney Disease: A Mechanistic Clinical Study. Kidney360. 2022 3(12):2036-2047. PMID: 36591354. PMCID: PMC9802560.
• Ware J. Murine models of glycoprotein Ib-IX. Platelets. 2022:1-6. PMID: 35417661.
• Malehmir M, Pfister D, Gallage S, [et al., including Ware J]. Author Correction: Platelet GPIbα is a mediator and potential interventional target for NASH and subsequent liver cancer. Nature medicine. 2022. PMID: 35181768.
• Corken A, Ghosh SP, Du R, [et al., including Ware J]. Platelet glycoprotein Ibα provides radiation protection. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 2021 167:143-148. PMID: 34971661. PMCID: PMC8934272.
• Jain N, Corken A, Kumar A, [et al., including Ware J]. Role of Platelets in Chronic Kidney Disease. Journal of the American Society of Nephrology : JASN. 2021. PMID: 34140394. PMCID: PMC8425650.
• Xiang B, Zhang G, Zhang Y, [et al., including Ware J]. Calcium Ion Chelation Preserves Platelet Function During Cold Storage. Arteriosclerosis, thrombosis, and vascular biology. 2020:ATVBAHA120314879. PMID: 33176450. PMCID: PMC8158249.
• Gupta S, Konradt C, Corken A, [et al., including Ware J]. Hemostasis vs. homeostasis: Platelets are essential for preserving vascular barrier function in the absence of injury or inflammation. Proceedings of the National Academy of Sciences of the United States of America. 2020 117(39):24316-24325. PMID: 32929010. PMCID: PMC7533880.
• Jain N, Wan F, Kothari M, [et al., including Ware J]. Association of platelet function with depression and its treatment with sertraline in patients with chronic kidney disease: analysis of a randomized trial. BMC nephrology. 2019 20(1):395. PMID: 31664940. PMCID: PMC6819518.