Steven R Post, PhD

Full Member

Research Program:

Cancer Biology

Faculty Rank:

Professor

Campus:

University of Arkansas for Medical Sciences

College:

College of Medicine

Department:

Pathology

Cancer Research Interest

Disease Site Focus: Breast, Leukemia/ Lymphoma
Research Focus Area: Treatment, Carcinogenesis, Diagnosis/ Prognosis
Type of Research: Basic
Research Interest Statement: My research interests relate to inhibiting cancer growth and metastasis by defining and targeting the pathways used by macrophages to recognize and respond to factors in the tumor microenvironment.

Contact Information

Email Address: SPOST@UAMS.EDU
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Active Grants

NIH/Nat. Heart, Lung & Blood Institute – 1R01HL162958
“Impact of hemodynamics on efferocytosis in endothelial cells”
Co-Investigator
04/01/22 – 03/31/27
NIH/Nat. Cancer Institute – 7R01CA228166
“Periodontal bacteria enhance oral KSHV pathogenesis and Kaposi's Sarcoma development in HIV + patients - Continuation”
Principal Investigator
05/01/19 – 04/30/24

Publications

Chen J, Lin Z, Song J, [et al., including Post SR]. Echinomycin as a promising therapeutic agent against KSHV-related malignancies. Journal of hematology & oncology. 2023 16(1):48. PMID: 37143124. PMCID: PMC10161613.
Chen J, Song J, Plaisance-Bonstaff K, [et al., including Post SR]. Role of Histamine and Related Signaling in Kaposi's Sarcoma-Associated Herpesvirus Pathogenesis and Oncogenesis. Viruses. 2023 15(4). PMID: 37112991. PMCID: PMC10142667.
Nounamo B, Jousheghany F, Siegel ER, [et al., including Post SR]. VT68.2: An Antibody to Chondroitin Sulfate Proteoglycan 4 (CSPG4) Displays Reactivity against a Tumor-Associated Carbohydrate Antigen. International journal of molecular sciences. 2023 24(3). PMID: 36768830. PMCID: PMC9917008.
Nakamura N, Rogers P, Eggerson R, [et al., including Post SR]. Translational Research for Identifying Potential Early-stage Prostate Cancer Biomarkers. Cancer genomics & proteomics. 2023 20(1):1-8. PMID: 36581341. PMCID: PMC9806668.
Nagalo BM, Zhou Y, Loeuillard EJ, [et al., including Post SR]. Characterization of Morreton virus as an oncolytic virotherapy platform for liver cancers. Hepatology (Baltimore, Md.). 2022. PMID: 36052732.
Chen J, Song J, Dai L, [et al., including Post SR]. SARS-CoV-2 infection and lytic reactivation of herpesviruses: A potential threat in the postpandemic era?. Journal of medical virology. 2022. PMID: 35819034. PMCID: PMC9350099.
Chen J, Dai L, Kendrick S, [et al., including Post SR]. The Anti-COVID-19 Drug Remdesivir Promotes Oncogenic Herpesvirus Reactivation through Regulation of Intracellular Signaling Pathways. Antimicrobial agents and chemotherapy. 2022:aac0239521. PMID: 35041508. PMCID: PMC8923226.
Dai L, Lu YC, Chen J, [et al., including Post SR]. Oral Shedding of an Oncogenic Virus Alters the Oral Microbiome in HIV+ Patients. Frontiers in microbiology. 2022 13:882520. PMID: 35516440. PMCID: PMC9063630.
Zhang Y, Gabere M, Taylor MA, [et al., including Post SR]. Repurposing live attenuated trivalent MMR vaccine as cost-effective cancer immunotherapy. Frontiers in oncology. 2022 12:1042250. PMID: 36457491. PMCID: PMC9706410.
Chen J, Song J, James J, [et al., including Post SR]. Activation of IL1 signaling molecules by Kaposi's sarcoma-associated herpesvirus. Frontiers in cellular and infection microbiology. 2022 12:1049624. PMID: 36457850. PMCID: PMC9705745.
Chen J, Dai L, Barrett L, [et al., including Post SR]. SARS-CoV-2 proteins and anti-COVID-19 drugs induce lytic reactivation of an oncogenic virus. Communications biology. 2021 4(1):682. PMID: 34083759. PMCID: PMC8175744.
Del Valle L, Dai L, Lin HY, [et al., including Post SR]. Role of EIF4G1 network in non-small cell lung cancers (NSCLC) cell survival and disease progression. Journal of cellular and molecular medicine. 2021. PMID: 33539648. PMCID: PMC7957206.
Dai L, Jung BG, Chen J, [et al., including Post SR]. The potential impacts of early secreted antigenic target of 6 kDa of Mycobacterium tuberculosis on KSHV-infected cells. Journal of medical virology. 2020. PMID: 32648938. PMCID: PMC7796979.
Chen J, Goyal N, Dai L, [et al., including Post S]. Developing new ceramide analogs and identifying novel sphingolipid-controlled genes against a virus-associated lymphoma. Blood. 2020. PMID: 32518949. PMCID: PMC7645984.
Murray GP, Post SR, Post GR. ABO blood group is a determinant of von Willebrand factor protein levels in human pulmonary endothelial cells. Journal of clinical pathology. 2020 73(6):347-349. PMID: 31662441. PMCID: PMC7279561.
Dai L, Forrest J, Barrett L, [et al., including Post SR]. Porphyromonas gingivalis coinfects with KSHV in oral cavities of HIV+ patients and induces viral lytic reactivation. Journal of medical virology. 2020. PMID: 32436999. PMCID: PMC7679274.
Dai L, Forrest J, Qiao J, [et al., including Post SR]. Kaposi Sarcoma-Associated Herpesvirus and Staphylococcus aureus Coinfection in Oral Cavities of HIV-Positive Patients: A Unique Niche for Oncogenic Virus Lytic Reactivation. The Journal of infectious diseases. 2020 221(8):1331-1341. PMID: 31111897. PMCID: PMC7325796.
Chen J, Forrest J, post s, [et al.]. Mechanistic Insights into Chemoresistance Mediated by Oncogenic Viruses in Lymphomas. Viruses. 2019 11(12). PMID: 31888174. PMCID: PMC6950054.
Chen J, Dai L, Goldstein A, [et al., including Post SR]. Identification of new antiviral agents against Kaposi's sarcoma-associated herpesvirus (KSHV) by high-throughput drug screening reveals the role of histamine-related signaling in promoting viral lytic reactivation. PLoS pathogens. 2019 15(12):e1008156. PMID: 31790497. PMCID: PMC6907871.
Chen J, Del Valle L, Lin HY, [et al., including Post SR]. Expression of PD-1 and PD-Ls in Kaposi's sarcoma and regulation by oncogenic herpesvirus lytic reactivation. Virology. 2019 536:16-19. PMID: 31394407. PMCID: PMC6733645.
Madan E, Pelham CJ, Nagane M, [et al., including Post SR]. Flower isoforms promote competitive growth in cancer. Nature. 2019 572(7768):260-264. PMID: 31341286.
Asfari A, post s, Dent JA, [et al.]. Platelet Glycoprotein VI Haplotypes and the Presentation of Paediatric Sepsis. Thrombosis and haemostasis. 2019 119(3):431-438. PMID: 30597490.
Chen J, Forrest J, post s, [et al.]. Transactivation of human endogenous retroviruses by tumor viruses and their functions in virus-associated malignancies. Oncogenesis. 2019 8(1):6. PMID: 30643113. PMCID: PMC6331641.
Post GR, Yuan Y, Holthoff ER, [et al., including Post SR]. Identification of a novel monocytic phenotype in Classic Hodgkin Lymphoma tumor microenvironment. PloS one. 2019 14(11):e0224621. PMID: 31714922. PMCID: PMC6850552.