Behjatolah M Karbassi, PhD

Research Program: Cancer Biology Faculty Rank: Associate Professor Campus: University of Arkansas for Medical Sciences College: College of Medicine Department: Pathology

Cancer Research Interest

• Disease Site Focus: Breast, Thoracic/ Lung
• Research Focus Area: Treatment
• Type of Research: Clinical
• Research Interest Statement: Cancer vaccine and immuno-oncology. Development of combination therapies for cancer treatment. Biomarkers of immune and clinical response to cancer vaccines and immunotherapy. Role of tumor-associated glycans in tumor progression and tumor-induced immune suppression. Breast cancer.

Contact Information

• Email Address: KARBASSI@UAMS.EDU
• Profiles Research Networking Software: View Profile

Publications

• Li W, Twaddle NC, Spray B, [et al., including Monzavi-Karbassi B]. Feeding Soy Protein Concentrates with Low and High Isoflavones Alters 9 and 18 Weeks Serum Isoflavones and Inflammatory Protein Levels in Lean and Obese Zucker Rats. Journal of medicinal food. 2023. PMID: 36720082.
• Nounamo B, Jousheghany F, Siegel ER, [et al., including Monzavi-Karbassi B]. VT68.2: An Antibody to Chondroitin Sulfate Proteoglycan 4 (CSPG4) Displays Reactivity against a Tumor-Associated Carbohydrate Antigen. International journal of molecular sciences. 2023 24(3). PMID: 36768830. PMCID: PMC9917008.
• Pashov A, Murali R, Makhoul I, [et al., including Karbassi B]. Harnessing Antibody Polyspecificity for Cancer Immunotherapy. Monoclonal antibodies in immunodiagnosis and immunotherapy. 2022 41(5):290-300. PMID: 36306515.
• Makhoul I, Ibrahim SM, Abu-Rmaileh M, [et al., including Monzavi-Karbassi B]. P10s-PADRE vaccine combined with neoadjuvant chemotherapy in ER-positive breast cancer patients induces humoral and cellular immune responses. Oncotarget. 2021 12(22):2252-2265. PMID: 34733416. PMCID: PMC8555684.
• Urbaniak A, Jousheghany F, Piña-Oviedo S, [et al., including Monzavi-Karbassi B]. Carbamate derivatives of colchicine show potent activity towards primary acute lymphoblastic leukemia and primary breast cancer cells-in vitro and ex vivo study. Journal of biochemical and molecular toxicology. 2020 34(6):e22487. PMID: 32141170.
• Hernandez Puente CV, Hsu PC, Rogers LJ, [et al., including Monzavi-Karbassi B]. Association of DNA-Methylation Profiles With Immune Responses Elicited in Breast Cancer Patients Immunized With a Carbohydrate-Mimicking Peptide: A Pilot Study. Frontiers in oncology. 2020 10:879. PMID: 32582547. PMCID: PMC7290046.
• Behrens A, Jousheghany F, Yao-Borengasser A, [et al., including Monzavi-Karbassi B]. Carbohydrate (Chondroitin 4) Sulfotransferase-11-Mediated Induction of Epithelial-Mesenchymal Transition and Generation of Cancer Stem Cells. Pharmacology. 2020 105(5-6):246-259. PMID: 32344408.
• Urbaniak A, Jousheghany F, Yuan Y, [et al., including Monzavi-Karbassi B]. The response of phyllodes tumor of the breast to anticancer therapy: An in vitro and ex vivo study. Oncology letters. 2019 18(5):5097-5106. PMID: 31612021. PMCID: PMC6781661.
• Pashov A, Hernandez Puente CV, Ibrahim SM, [et al., including Monzavi-Karbassi B]. Thinking Cancer. Monoclonal antibodies in immunodiagnosis and immunotherapy. 2018 37(3):117-125. PMID: 29939836.
• Hutchins LF, Makhoul I, Emanuel PD, [et al., including Monzavi-Karbassi B]. Targeting tumor-associated carbohydrate antigens: a phase I study of a carbohydrate mimetic-peptide vaccine in stage IV breast cancer subjects. Oncotarget. 2017 8(58):99161-99178. PMID: 29228761. PMCID: PMC5716801.
• Kieber-Emmons T, Monzavi-Karbassi B, Hutchins LF, [et al.]. Harnessing benefit from targeting tumor associated carbohydrate antigens. Human vaccines & immunotherapeutics. 2017 13(2):323-331. PMID: 27929800. PMCID: PMC5328237.
• Kieber-Emmons T, Makhoul I, Pennisi A, [et al., including Monzavi-Karbassi B]. Managing Expectations in the Transition to Proof of Concept Studies. Reviews on recent clinical trials. 2017 12(2):111-123. PMID: 28325150. PMCID: PMC9252264.
• Monzavi-Karbassi B, Jousheghany F, Kieber-Emmons T. Tumor-associated Glycans and Tregs in Immunogenicity of an Autologous Cell-based Vaccine. Immunological investigations. 2016 45(8):746-758. PMID: 27759476.
• Monzavi-Karbassi B, Siegel ER, Medarametla S, [et al.]. Breast cancer survival disparity between African American and Caucasian women in Arkansas: A race-by-grade analysis. Oncology letters. 2016 12(2):1337-1342. PMID: 27446434. PMCID: PMC4950488.