Behjatolah M Karbassi, PhD

Research Program: Cancer Biology Faculty Rank: Associate Professor Campus: University of Arkansas for Medical Sciences College: College of Medicine Department: Pathology Research Faculty

Cancer Research Interest

• Disease Site Focus: Breast, Thoracic/ Lung
• Research Focus Area: Treatment
• Type of Research: Clinical
• Research Interest Statement: Cancer vaccine and immuno-oncology. Development of combination therapies for cancer treatment. Biomarkers of immune and clinical response to cancer vaccines and immunotherapy. Role of tumor-associated glycans in tumor progression and tumor-induced immune suppression. Breast cancer.

Contact Information

• Email Address: KARBASSI@UAMS.EDU
• Profiles Research Networking Software: View Profile

Active Grants

• NIH/Nat. Cancer Institute – 1R21CA280448
  “SR-A as a therapeutic target in breast cancer”
  Principal Investigator
  1/1/2024 – 12/31/2025

Recent Publications

• Monzavi-Karbassi B, Kelly T, Post SR. The Tumor Microenvironment and Immune Response in Breast Cancer. International journal of molecular sciences. 2024 25(2). PMID: 38255987. PMCID: PMC10815817.
• Chen J, Lin Z, Fan J, [et al., including Monzavi-Karbassi B]. Identification of new microtubule small-molecule inhibitors and microtubule-associated genes against triple negative breast cancer. American journal of cancer research. 2024 14(4):1545-1560. PMID: 38726264. PMCID: PMC11076258.
• Li W, Twaddle NC, Spray B, [et al., including Monzavi-Karbassi B]. Feeding Soy Protein Concentrates with Low and High Isoflavones Alters 9 and 18 Weeks Serum Isoflavones and Inflammatory Protein Levels in Lean and Obese Zucker Rats. Journal of medicinal food. 2023. PMID: 36720082.
• Nounamo B, Jousheghany F, Siegel ER, [et al., including Monzavi-Karbassi B]. VT68.2: An Antibody to Chondroitin Sulfate Proteoglycan 4 (CSPG4) Displays Reactivity against a Tumor-Associated Carbohydrate Antigen. International journal of molecular sciences. 2023 24(3). PMID: 36768830. PMCID: PMC9917008.
• Pashov A, Murali R, Makhoul I, [et al., including Karbassi B]. Harnessing Antibody Polyspecificity for Cancer Immunotherapy. Monoclonal antibodies in immunodiagnosis and immunotherapy. 2022 41(5):290-300. PMID: 36306515.
• Makhoul I, Ibrahim SM, Abu-Rmaileh M, [et al., including Monzavi-Karbassi B]. P10s-PADRE vaccine combined with neoadjuvant chemotherapy in ER-positive breast cancer patients induces humoral and cellular immune responses. Oncotarget. 2021 12(22):2252-2265. PMID: 34733416. PMCID: PMC8555684.
• Urbaniak A, Jousheghany F, Piña-Oviedo S, [et al., including Monzavi-Karbassi B]. Carbamate derivatives of colchicine show potent activity towards primary acute lymphoblastic leukemia and primary breast cancer cells-in vitro and ex vivo study. Journal of biochemical and molecular toxicology. 2020 34(6):e22487. PMID: 32141170.
• Hernandez Puente CV, Hsu PC, Rogers LJ, [et al., including Monzavi-Karbassi B]. Association of DNA-Methylation Profiles With Immune Responses Elicited in Breast Cancer Patients Immunized With a Carbohydrate-Mimicking Peptide: A Pilot Study. Frontiers in oncology. 2020 10:879. PMID: 32582547. PMCID: PMC7290046.
• Behrens A, Jousheghany F, Yao-Borengasser A, [et al., including Monzavi-Karbassi B]. Carbohydrate (Chondroitin 4) Sulfotransferase-11-Mediated Induction of Epithelial-Mesenchymal Transition and Generation of Cancer Stem Cells. Pharmacology. 2020 105(5-6):246-259. PMID: 32344408.