Angus MacNicol, PhD
Full Member
| Research Program:
Cancer Biology
Faculty Rank:
Professor
Campus:
University of Arkansas for Medical Sciences
College:
College of Medicine
Department:
Neurobiology & Developmental Science
|
Contact Information
- Email Address: ANGUS@UAMS.EDU
- Profiles Research Networking Software: View Profile
Active Grants
- NIH/Nat. Inst. of Diabetes & Digestive & Kidney Diseases – 1R01DK127723“The Impact of Obesity on Somatotrope Function”Co-Investigator07/01/21 – 06/30/25
- NIH/Nat. Inst. of Child Health & Human Development – 1R01HD093461“Control of pituitary cell plasticity through regulated mRNA translation”Principal Investigator09/01/18 – 06/30/23
Publications
- Urbaniak A, Reed MR, Heflin B, [et al., including MacNicol AM]. Anti-glioblastoma activity of monensin and its analogs in an organoid model of cancer. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2022 153:113440. PMID: 36076555. PMCID: PMC9472755.
- Urbaniak A, Reed MR, Fil D, [et al., including MacNicol AM]. Single and double modified salinomycin analogs target stem-like cells in 2D and 3D breast cancer models. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2021 141:111815. PMID: 34130123. PMCID: PMC8429223.
- Ruf-Zamojski F, MacNicol A, Zhang Z, [et al.]. Single nucleus multi-omics regulatory landscape of the murine pituitary. Nature communications. 2021 12(1):2677. PMID: 33976139. PMCID: PMC8113460.
- Odle AK, MacNicol MC, Childs GV, MacNicol AM. Post-Transcriptional Regulation of Gnrhr: A Checkpoint for Metabolic Control of Female Reproduction. International journal of molecular sciences. 2021 22(7). PMID: 33805020. PMCID: PMC8038027.
- Allensworth-James M, Banik J, Odle A, [et al., including MacNicol AM]. Control of the Anterior Pituitary Cell Lineage Regulator POU1F1 by the Stem Cell Determinant Musashi. Endocrinology. 2021 162(3). PMID: 33570120.
- Allensworth-James M, Banik J, Odle A, [et al., including MacNicol AM]. Control of the Anterior Pituitary Cell Lineage Regulator POU1F1 by the Stem Cell Determinant Musashi. Endocrinology. 2021 162(3). PMID: 33373440. PMCID: PMC7814296.
- Miles TK, Silva Moreira AR, Allensworth-James ML, [et al., including MacNicol AM]. Sex differences in somatotrope response to fasting: biphasic responses in male mice. The Journal of endocrinology. 2020 247(3):213-224. PMID: 33112825. PMCID: PMC7673470.
- Childs GV, Odle AK, MacNicol MC, MacNicol AM. The Importance of Leptin to Reproduction. Endocrinology. 2020. PMID: 33165520. PMCID: PMC7749705.
- Allensworth-James ML, Odle AK, Lim J, [et al., including MacNicol AM]. Metabolic signalling to somatotrophs: Transcriptional and post-transcriptional mediators. Journal of neuroendocrinology. 2020:e12883. PMID: 32657474. PMCID: PMC8086172.
- Childs GV, MacNicol AM, MacNicol MC. Molecular Mechanisms of Pituitary Cell Plasticity. Frontiers in endocrinology. 2020 11:656. PMID: 33013715. PMCID: PMC7511515.
- MacNicol AM, Odle AK, Childs GV. ELAVL1 Elevates Insights: The Ups and Downs of Regulated mRNA Translation in the Control of Gonadotropin Release. Endocrinology. 2019 160(10):2466-2468. PMID: 31504402. PMCID: PMC6760528.
- Zhao S, Zhu Y, Schultz RD, [et al., including Macnicol A]. Partial Leptin Reduction as an Insulin Sensitization and Weight Loss Strategy. Cell metabolism. 2019 30(4):706-719.e6. PMID: 31495688. PMCID: PMC6774814.
- Cragle CE, MacNicol MC, Byrum SD, [et al., including MacNicol AM]. Musashi interaction with poly(A)-binding protein is required for activation of target mRNA translation. The Journal of biological chemistry. 2019 294(28):10969-10986. PMID: 31152063. PMCID: PMC6635449.
- Allensworth-James ML, Odle A, Haney A, [et al., including MacNicol A]. Sex-specific changes in postnatal GH and PRL secretion in somatotrope LEPR-null mice. The Journal of endocrinology. 2018 238(3):221-230. PMID: 29929987. PMCID: PMC6354591.
- Odle AK, Bene? H, Melgar Castillo A, [et al., including MacNicol AM]. Association of Gnrhr mRNA With the Stem Cell Determinant Musashi: A Mechanism for Leptin-Mediated Modulation of GnRHR Expression. Endocrinology. 2018 159(2):883-894. PMID: 29228137. PMCID: PMC5776477.
- MacNicol MC, Cragle CE, McDaniel FK, [et al., including MacNicol AM]. Evasion of regulatory phosphorylation by an alternatively spliced isoform of Musashi2. Scientific reports. 2017 7(1):11503. PMID: 28912529. PMCID: PMC5599597.
- Odle AK, Akhter N, Syed MM, [et al., including MacNicol AM]. Leptin Regulation of Gonadotrope Gonadotropin-Releasing Hormone Receptors As a Metabolic Checkpoint and Gateway to Reproductive Competence. Frontiers in endocrinology. 2017 8:367. PMID: 29354094. PMCID: PMC5760501.
- Odle AK, Allensworth-James ML, Akhter N, [et al., including MacNicol AM]. A Sex-Dependent, Tropic Role for Leptin in the Somatotrope as a Regulator of POU1F1 and POU1F1-Dependent Hormones. Endocrinology. 2016 157(10):3958-3971. PMID: 27571135. PMCID: PMC5045503.
- Byrd AK, Zybailov BL, Maddukuri L, [et al., including MacNicol AM]. Evidence That G-quadruplex DNA Accumulates in the Cytoplasm and Participates in Stress Granule Assembly in Response to Oxidative Stress. The Journal of biological chemistry. 2016 291(34):18041-57. PMID: 27369081. PMCID: PMC5016190.