Antino R Allen, PhD

Research Program: Cancer Therapeutics Faculty Rank: Professor Campus: University of Arkansas for Medical Sciences College: College of Pharmacy Department: Radiation Health

Contact Information

• Email Address: ARALLEN@UAMS.EDU
• Profiles Research Networking Software: View Profile

Active Grants

• NIH/Nat. Inst. of General Medical Sciences – 1T32GM152782
  “Initiative for Maximizing Student Development (IMSD)”
  Principal Investigator
  2/1/2024 – 1/31/2029
• Arkansas Research Alliance – AWD00055633
  “Arkansas Research Alliance”
  Principal Investigator
  1/23/2023 – 1/22/2026
• NIH/Nat. Cancer Institute – 1R01CA258673
  “MnBuOE as a Novel Chemosensitizer for Breast Cancer and Neuroprotector”
  Principal Investigator
  8/1/2021 – 7/31/2025

Recent Publications

• Anders ME, Prince LY, Williams TB, [et al., including Allen AR]. Summer undergraduate biomedical research program for underrepresented minority students in a rural, low-income state. Frontiers in public health. 2024 12:1395942. PMID: 38846599. PMCID: PMC11153754.
• Otoo RA, Allen AR. Sulforaphane's Multifaceted Potential: From Neuroprotection to Anticancer Action. Molecules (Basel, Switzerland). 2023 28(19). PMID: 37836745. PMCID: PMC10574530.
• Allen AR, Jones A', LoBianco FV, [et al.]. Effect of Sirt3 on hippocampal MnSOD activity, mitochondrial function, physiology, and cognition in an aged murine model. Behavioural brain research. 2023 444:114335. PMID: 36804441. PMCID: PMC10081808.
• Nemec-Bakk AS, Sridharan V, Desai P, [et al., including Allen AR]. Effects of Simulated 5-Ion Galactic Cosmic Radiation on Function and Structure of the Mouse Heart. Life (Basel, Switzerland). 2023 13(3). PMID: 36983950. PMCID: PMC10057791.
• Prince LY, Williams TB, Allen AR, [et al.]. Outcomes of the UAMS summer undergraduate research program to increase diversity in research and health professions. Advances in physiology education. 2023 47(1):20-25. PMID: 36326474. PMCID: PMC9762971.
• Corley C, McElroy T, Sridharan B, [et al., including Allen AR]. Physiological and cognitive changes after treatments of cyclophosphamide, methotrexate, and fluorouracil: implications of the gut microbiome and depressive-like behavior. Frontiers in neuroscience. 2023 17:1212791. PMID: 37869506. PMCID: PMC10587567.
• Trujillo M, Odle AK, Aykin-Burns N, Allen AR. Chemotherapy induced oxidative stress in the ovary: drug-dependent mechanisms and potential interventions†. Biology of reproduction. 2022. PMID: 36539327. PMCID: PMC10106837.
• Rubinstein L, Kiffer F, Puukila S, [et al., including Allen AR]. Mitochondria-Targeted Human Catalase in the Mouse Longevity MCAT Model Mitigates Head-Tilt Bedrest-Induced Neuro-Inflammation in the Hippocampus. Life (Basel, Switzerland). 2022 12(11). PMID: 36362993. PMCID: PMC9695374.
• Simmons P, Corley C, Allen AR. Fractionated Proton Irradiation Does Not Impair Hippocampal-Dependent Short-Term or Spatial Memory in Female Mice. Toxics. 2022 10(9). PMID: 36136472. PMCID: PMC9503909.
• Ntagwabira F, Trujillo M, McElroy T, [et al., including Allen AR]. Piperlongumine as a Neuro-Protectant in Chemotherapy Induced Cognitive Impairment. International journal of molecular sciences. 2022 23(4). PMID: 35216124. PMCID: PMC8880369.
• LoBianco FV, Krager KJ, Johnson E, [et al., including Allen AR]. Parthenolide induces rapid thiol oxidation that leads to ferroptosis in hepatocellular carcinoma cells. Frontiers in toxicology. 2022 4:936149. PMID: 36591540. PMCID: PMC9795200.
• Simmons P, Trujillo M, McElroy T, [et al., including Allen AR]. Evaluating the effects of low-dose simulated galactic cosmic rays on murine hippocampal-dependent cognitive performance. Frontiers in neuroscience. 2022 16:908632. PMID: 36561122. PMCID: PMC9765097.
• Kim HN, Richardson KK, Krager KJ, [et al., including Allen AR]. Simulated Galactic Cosmic Rays Modify Mitochondrial Metabolism in Osteoclasts, Increase Osteoclastogenesis and Cause Trabecular Bone Loss in Mice. International journal of molecular sciences. 2021 22(21). PMID: 34769141. PMCID: PMC8583929.
• Trujillo M, McElroy T, Brown T, [et al., including Allen AR]. Combined Mechanical and Enzymatic Dissociation of Mouse Brain Hippocampal Tissue. Journal of visualized experiments : JoVE. 2021(176). PMID: 34747412. PMCID: PMC9208324.
• Trujillo M, Kharbanda A, Corley C, [et al., including Allen AR]. Tocotrienols as an Anti-Breast Cancer Agent. Antioxidants (Basel, Switzerland). 2021 10(9). PMID: 34573015. PMCID: PMC8472290.
• Rubinstein L, Schreurs AS, Torres SM, [et al., including Allen AR]. Overexpression of catalase in mitochondria mitigates changes in hippocampal cytokine expression following simulated microgravity and isolation. NPJ microgravity. 2021 7(1):24. PMID: 34230490. PMCID: PMC8260663.
• Swinton C, Kiffer F, McElroy T, [et al., including Allen AR]. Effects of (16)O charged-particle irradiation on cognition, hippocampal morphology and mutagenesis in female mice. Behavioural brain research. 2021 407:113257. PMID: 33794227.
• Brown T, Boerma M, McElroy T, [et al., including Allen AR]. Cognitive impairment resulting from treatment with docetaxel, doxorubicin, and cyclophosphamide. Brain research. 2021 1760:147397. PMID: 33705788. PMCID: PMC9179831.
• Brown T, Sykes D, Allen AR. Implications of Breast Cancer Chemotherapy-Induced Inflammation on the Gut, Liver, and Central Nervous System. Biomedicines. 2021 9(2). PMID: 33668580. PMCID: PMC7917715.
• Hendrix RD, Ou Y, Davis JE, [et al., including Allen AR]. Alzheimer amyloid-β- peptide disrupts membrane localization of glucose transporter 1 in astrocytes: implications for glucose levels in brain and blood. Neurobiology of aging. 2021 97:73-88. PMID: 33161213. PMCID: PMC7736209.
• Williams TB, Prince LY, Allen AR, [et al.]. Performance measures of racially underrepresented Ph.D. students in biomedical sciences: The UAMS IMSD Program Outcomes. PloS one. 2021 16(2):e0246683. PMID: 33556126. PMCID: PMC7870087.
• Davis CM, Allen AR, Bowles DE. Consequences of space radiation on the brain and cardiovascular system. Journal of environmental science and health. Part C, Toxicology and carcinogenesis. 2021 39(2):180-218. PMID: 33902387.
• Corley C, Allen AR. A Bibliometric Analysis of Cyclophosphamide, Methotrexate, and Fluorouracil Breast Cancer Treatments: Implication for the Role of Inflammation in Cognitive Dysfunction. Frontiers in molecular biosciences. 2021 8:683389. PMID: 34490346. PMCID: PMC8417522.
• Groves T, Corley C, Byrum SD, Allen AR. The Effects of 5-Fluorouracil/Leucovorin Chemotherapy on Cognitive Function in Male Mice. Frontiers in molecular biosciences. 2021 8:762116. PMID: 34778377. PMCID: PMC8581634.
• Newton J, Brown T, Corley C, [et al., including Allen AR]. Cranial irradiation impairs juvenile social memory and modulates hippocampal physiology. Brain research. 2020 1748:147095. PMID: 32896524. PMCID: PMC7602883.
• Simmons P, McElroy T, Allen AR. A Bibliometric Review of Artificial Extracellular Matrices Based on Tissue Engineering Technology Literature: 1990 through 2019. Materials (Basel, Switzerland). 2020 13(13). PMID: 32605069. PMCID: PMC7372414.
• McElroy T, Allen AR. A Bibliometric Review of Publications on Oxidative Stress and Chemobrain: 1990-2019. Antioxidants (Basel, Switzerland). 2020 9(5). PMID: 32443630. PMCID: PMC7278845.
• McElroy T, Brown T, Kiffer F, [et al., including Allen AR]. Assessing the Effects of Redox Modifier MnTnBuOE-2-PyP 5+ on Cognition and Hippocampal Physiology Following Doxorubicin, Cyclophosphamide, and Paclitaxel Treatment. International journal of molecular sciences. 2020 21(5). PMID: 32182883. PMCID: PMC7084440.
• Anderson JE, Trujillo M, McElroy T, [et al., including Allen AR]. Early Effects of Cyclophosphamide, Methotrexate, and 5-Fluorouracil on Neuronal Morphology and Hippocampal-Dependent Behavior in a Murine Model. Toxicological sciences : an official journal of the Society of Toxicology. 2020 173(1):156-170. PMID: 31651976. PMCID: PMC8204947.
• Kiffer F, Alexander T, Anderson J, [et al., including Allen A]. Late Effects of (1)H + (16)O on Short-Term and Object Memory, Hippocampal Dendritic Morphology and Mutagenesis. Frontiers in behavioral neuroscience. 2020 14:96. PMID: 32670032. PMCID: PMC7332779.